Effect of Continuing Versus Holding Metformin During Hospitalizations.

Description

A randomized study of continuing versus holding metformin during hospitalizations to internal medicine services to determine the effects on glucose control, acidosis, abdominal symptoms, length of stay, and mortality.

Conditions

Diabetes Mellitus, Type 2

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Study Overview

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Study Details

Study overview

A randomized study of continuing versus holding metformin during hospitalizations to internal medicine services to determine the effects on glucose control, acidosis, abdominal symptoms, length of stay, and mortality.

Effect of Continuing Versus Holding Metformin During Hospitalizations to Internal Medicine on Glucose Control, Acidosis, Abdominal Symptoms, Length of Stay, and Mortality.

Effect of Continuing Versus Holding Metformin During Hospitalizations.

Condition
Diabetes Mellitus, Type 2
Intervention / Treatment

-

Contacts and Locations

Chicago

University of Illinois at Chicago, Chicago, Illinois, United States, 60612

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

  • * Adult (18+ years of age)
  • * Admitted to an internal medicine service.
  • * On Metformin prior to admission.
  • * Inability to take oral medications
  • * eGFR \< 30 ml/min/1.73 m2
  • * Dialysis
  • * Current Acidosis (pH \< 7.35) including diabetic ketoacidosis
  • * Child-Turcotte-Pugh class C hepatic cirrhosis
  • * Acute Decompensated Heart Failure
  • * Cognitively impaired and/or unable to consent
  • * Lack of or unwillingness to share contact information
  • * Pregnant women

Ages Eligible for Study

18 Years to 110 Years

Sexes Eligible for Study

ALL

Accepts Healthy Volunteers

No

Collaborators and Investigators

University of Illinois at Chicago,

Study Record Dates

2026-06-30