Descartes-15 for Patients With Relapsed/Refractory Multiple Myeloma

Description

This is a Phase I dose-escalation study to evaluate the safety, tolerability and preliminary efficacy of an autologous BCMA-targeting RNA-engineered CAR T-cell therapy in patients with Relapsed/Refractory Multiple Myeloma. The cell product is referred to as Descartes-15

Conditions

Refractory Multiple Myeloma, Relapsed Multiple Myeloma

Study Overview

Study Details

Study overview

This is a Phase I dose-escalation study to evaluate the safety, tolerability and preliminary efficacy of an autologous BCMA-targeting RNA-engineered CAR T-cell therapy in patients with Relapsed/Refractory Multiple Myeloma. The cell product is referred to as Descartes-15

Descartes-15 for Patients With Relapsed/Refractory Multiple Myeloma

Descartes-15 for Patients With Relapsed/Refractory Multiple Myeloma

Condition
Refractory Multiple Myeloma
Intervention / Treatment

-

Contacts and Locations

Bethesda

Center for Cancer and Blood Disorders (AON), Bethesda, Maryland, United States, 20817

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

    Ages Eligible for Study

    18 Years to

    Sexes Eligible for Study

    ALL

    Accepts Healthy Volunteers

    No

    Collaborators and Investigators

    Cartesian Therapeutics,

    Study Record Dates

    2027-10-01