RECRUITING

Evaluating Use of Topical Imipramine and Amitriptyline in Reducing Ultraviolet B Light-Induced Redness in Patients With Rosacea

Conditions

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

Rosacea is a common skin condition associated with easy blushing and red face; many patients with rosacea react to sunlight with increased redness. The purpose of this study is to determine if the use of a topical medication will help reduce sunlight induced redness and irritation in patients with rosacea.

Official Title

Pilot Studies Evaluating Use of Topical Imipramine and Amitriptyline in Reducing Ultraviolet B Light-Induced Redness in Patients With Rosacea

Quick Facts

Study Start:2024-02-27
Study Completion:2028-12
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT06312813

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:18 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:Yes
Standard Ages:ADULT, OLDER_ADULT
Inclusion CriteriaExclusion Criteria
  1. * Fitzpatrick Skin Type I - IIII
  2. * Self-identified rosacea or no history of flushing/blushing for controls
  3. * Able to provide medical history and list of medications -- control subjects will not be allowed to take medications that are known to be photosensitizers.
  1. * Using imipramine, amitriptyline or any other tricyclic antidepressant (oral or topical)
  2. * Using topical anti-inflammatory (within 1 week) or systemic agents (e.g. prednisone)
  3. * Large tattoos in the designated testing areas
  4. * Tanning bed use within last 3 months
  5. * Photodynamic Therapy or UCB treatments in past 3 months
  6. * Female Subjects: pregnant or nursing

Contacts and Locations

Study Contact

Manager Clinical Research Operations
CONTACT
(937)-245-7500
pturesearch@wrightstatephysicians.org

Study Locations (Sites)

Wright State Physicians
Fairborn, Ohio, 45324
United States

Collaborators and Investigators

Sponsor: Wright State University

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2024-02-27
Study Completion Date2028-12

Study Record Updates

Study Start Date2024-02-27
Study Completion Date2028-12

Terms related to this study

Additional Relevant MeSH Terms

  • Rosacea