Evaluating Use of Topical Imipramine and Amitriptyline in Reducing Ultraviolet B Light-Induced Redness in Patients With Rosacea

Description

Rosacea is a common skin condition associated with easy blushing and red face; many patients with rosacea react to sunlight with increased redness. The purpose of this study is to determine if the use of a topical medication will help reduce sunlight induced redness and irritation in patients with rosacea.

Conditions

Rosacea

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Study Overview

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Study Details

Study overview

Rosacea is a common skin condition associated with easy blushing and red face; many patients with rosacea react to sunlight with increased redness. The purpose of this study is to determine if the use of a topical medication will help reduce sunlight induced redness and irritation in patients with rosacea.

Pilot Studies Evaluating Use of Topical Imipramine and Amitriptyline in Reducing Ultraviolet B Light-Induced Redness in Patients With Rosacea

Evaluating Use of Topical Imipramine and Amitriptyline in Reducing Ultraviolet B Light-Induced Redness in Patients With Rosacea

Condition
Rosacea
Intervention / Treatment

-

Contacts and Locations

Fairborn

Wright State Physicians, Fairborn, Ohio, United States, 45324

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

  • * Fitzpatrick Skin Type I - IIII
  • * Self-identified rosacea or no history of flushing/blushing for controls
  • * Able to provide medical history and list of medications -- control subjects will not be allowed to take medications that are known to be photosensitizers.
  • * Using imipramine, amitriptyline or any other tricyclic antidepressant (oral or topical)
  • * Using topical anti-inflammatory (within 1 week) or systemic agents (e.g. prednisone)
  • * Large tattoos in the designated testing areas
  • * Tanning bed use within last 3 months
  • * Photodynamic Therapy or UCB treatments in past 3 months
  • * Female Subjects: pregnant or nursing

Ages Eligible for Study

18 Years to

Sexes Eligible for Study

ALL

Accepts Healthy Volunteers

Yes

Collaborators and Investigators

Wright State University,

Study Record Dates

2028-12