Determination of Baseline Levels for Prostate Cancer-Derived Extracellular Vesicles Following Local Treatment of Prostate Cancer

Description

This study is being done to determine whether levels of prostate cancer derived extracellular vesicles from blood and urine specimens correlate with response to primary local treatment (surgery) in prostate cancer.

Conditions

Prostate Carcinoma

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Study Overview

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Study Details

Study overview

This study is being done to determine whether levels of prostate cancer derived extracellular vesicles from blood and urine specimens correlate with response to primary local treatment (surgery) in prostate cancer.

Determination of Baseline Levels for Prostate Cancer-Derived Extracellular Vesicles Following Local Treatment of Prostate Cancer

Determination of Baseline Levels for Prostate Cancer-Derived Extracellular Vesicles Following Local Treatment of Prostate Cancer

Condition
Prostate Carcinoma
Intervention / Treatment

-

Contacts and Locations

Rochester

Mayo Clinic in Rochester, Rochester, Minnesota, United States, 55905

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

  • * \* PROSTATE CANCER PATIENTS:
  • * Age 18+
  • * Able to give informed consent
  • * Patients with prostate cancer
  • * Patients treated with primary prostatectomy
  • * The focus will be on high-risk patients with at least one of either criterion:
  • * PSA \>= 20 ng/ml
  • * AND/OR Gleason \>= 8
  • * AND/OR clinical stage \>= T3
  • * \* FEMALE CONTROL PATIENTS:
  • * Age 18+
  • * Able to give informed consent
  • * \* PROSTATE CANCER PATIENTS:
  • * Unable or unwilling to provide informed consent
  • * Metastatic prostate cancer - defined evidence of metastatic disease on pre-procedural testing
  • * \* FEMALE CONTROL PATIENTS:
  • * Unable or unwilling to provide informed consent

Ages Eligible for Study

18 Years to

Sexes Eligible for Study

ALL

Accepts Healthy Volunteers

Yes

Collaborators and Investigators

Mayo Clinic,

Eugene D. Kwon, M.D., PRINCIPAL_INVESTIGATOR, Mayo Clinic in Rochester

Study Record Dates

2025-07-01