RECRUITING

CAPABLE Transplant

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

The purpose of this mixed methods study is to adapt CAPABLE as CAPABLE Transplant to accomplish two things: 1) To resolve barriers to being classified as active on the Kidney Transplant (KT) waitlist, 2) as a surgical prehabilitation intervention targeting the pre-frail/ frail KT waitlist population. It consists of two phases- an open label pilot and a randomized waitlist control trial, and 3) pilot test the feasibility and acceptability for CAPABLE Transplant in symptom and waitlist specific metrics amongst low-income active kidney transplant waitlist candidates.

Official Title

Addressing Inactive Kidney Transplant Waitlist Status Through Adapting a Tailored Psycho-Social-Environmental Program

Quick Facts

Study Start:2025-01-25
Study Completion:2026-07-01
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT06326905

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:18 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:No
Standard Ages:ADULT, OLDER_ADULT
Inclusion CriteriaExclusion Criteria
  1. * Deceased Donor Waitlist
  2. * ≥18 years old
  3. * Community dwelling
  4. * Current Inactive status or active and had been inactive in the last 18 months for cardiovascular disease, frailty, obesity, social support, mental health, incomplete testing OR Active on the waitlist and low-income
  1. * Living Donor Waitlist
  2. * Severe cognitive impairment
  3. * Inactivity expected to last \> 3 months (eg cancer treatment)
  4. * \>4 hospitalizations in the last 12 months
  5. * Current home nursing, physical or occupational therapy

Contacts and Locations

Study Contact

Samantha Curriero, MPH
CONTACT
4436991220
scurrie6@jh.edu

Principal Investigator

Melissa Hladek, PhD
PRINCIPAL_INVESTIGATOR
Johns Hopkins School of Nursing

Study Locations (Sites)

Johns Hopkins School of Nursing
Baltimore, Maryland, 21205
United States

Collaborators and Investigators

Sponsor: Johns Hopkins University

  • Melissa Hladek, PhD, PRINCIPAL_INVESTIGATOR, Johns Hopkins School of Nursing

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2025-01-25
Study Completion Date2026-07-01

Study Record Updates

Study Start Date2025-01-25
Study Completion Date2026-07-01

Terms related to this study

Keywords Provided by Researchers

  • Activities of Daily Living
  • Instrumental Activities of Daily Living
  • Physical Function
  • Executive Function
  • Home
  • Intervention
  • Kidney Transplant
  • End Stage Renal Disease

Additional Relevant MeSH Terms

  • Quality of Life
  • Depression
  • End Stage Renal Disease
  • Disability Physical