RECRUITING

Caffeine Use in the Management of Preterm Infants

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Conditions

Apnea of PrematurityFeedingCaffeine

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Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

This study aims to assess whether extending the duration of caffeine therapy will help preterm infants achieve full oral feeding faster.

Official Title

Caffeine Use in the Management of Preterm Infants

Quick Facts

Study Start:2024-02-22
Study Completion:2026-12-31
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT06327152

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:1 Week to 40 Weeks
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:No
Standard Ages:CHILD
Inclusion CriteriaExclusion Criteria
  1. * Equal to or greater than 34 weeks and 0 days corrected gestation at time of enrollment.
  2. * Off respiratory support for at least 2 days (nasal canula oxygen, high flow nasal canula, continuous positive airway pressure (CPAP), mechanical ventilation).
  3. * On caffeine and meet criteria to discontinue caffeine.
  4. * No significant cardiopulmonary events for at least 5 days (apnea \> 20 seconds, apnea with heart rate (HR) \< 80 beats per minute (bpm), HR \< 80 bpm with desaturation \< 85% or color change).
  1. * Infants with critical congenital heart disease.
  2. * Infants with neuromuscular conditions affecting respiration.
  3. * Infants with overt brain injury (i.e. severe Grade 3-4 intraventricular hemorrhage, cystic periventricular leukomalacia) that may affect oral feeding.
  4. * Infants with major genetic disorders.
  5. * Infants with anatomic anomalies that will hinder oral feeding.
  6. * Infants who have already progressed to Step 3 (of 5) of our institution's oral feeding protocol (oral feeds 4 times per day).
  7. * Infants who develop necrotizing enterocolitis after enrollment.
  8. * Failure to obtain consent or declined by parents.

Contacts and Locations

Study Contact

Rosie Magallon
CONTACT
714-509-6082
rmagallo@hs.uci.edu

Principal Investigator

Cherry Uy, MD
PRINCIPAL_INVESTIGATOR
UC Irvine

Study Locations (Sites)

UC Irvine Medical Center
Orange, California, 92868
United States

Collaborators and Investigators

Sponsor: University of California, Irvine

  • Cherry Uy, MD, PRINCIPAL_INVESTIGATOR, UC Irvine

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2024-02-22
Study Completion Date2026-12-31

Study Record Updates

Study Start Date2024-02-22
Study Completion Date2026-12-31

Terms related to this study

Keywords Provided by Researchers

  • Feeding
  • Caffeine

Additional Relevant MeSH Terms

  • Apnea of Prematurity