Zinc and Iron Absorption From Common Beans in Young Adult Women

Description

Fifteen female study participants will be enrolled in a randomized crossover study to measure fractional and total zinc and iron absorption from four common bean (Phaseolus vulgaris) varieties with varying phytate and polyphenolic contents. Phytate, the storage form of phosphorus in plants, and polyphenols, which contribute to the varied colors of common beans, are natural components of the beans and can reduce zinc and iron bioavailability from these foods.

Conditions

Zinc Absorption, Iron Absorption

Study Overview

Study Details

Study overview

Fifteen female study participants will be enrolled in a randomized crossover study to measure fractional and total zinc and iron absorption from four common bean (Phaseolus vulgaris) varieties with varying phytate and polyphenolic contents. Phytate, the storage form of phosphorus in plants, and polyphenols, which contribute to the varied colors of common beans, are natural components of the beans and can reduce zinc and iron bioavailability from these foods.

Zinc and Iron Absorption From Common Beans in Young Adult Women

Zinc and Iron Absorption From Common Beans in Young Adult Women

Condition
Zinc Absorption
Intervention / Treatment

-

Contacts and Locations

Davis

Department of Nutrition, Davis, California, United States, 95616

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

  • * Healthy eumenorrheic (regular monthly menstrual cycles of 25-30-days in length)
  • * BMI 18.5 - 30 kg/m2
  • * Regular consumer of beans, i.e. ≥ 4 servings per month
  • * Usual iron intake estimated by Food Frequency Questionnaire to be less than the Recommended Daily Allowance (RDA) of 18 mg/d (8)
  • * Subject is willing and able to comply with the study protocols.
  • * Subject is willing to participate in all study procedures.
  • * Dislike or allergy to beans
  • * Self-reported current or recent pregnancy (within the past 12 months)
  • * Self-reported recent termination of pregnancy (3 months if abortion in 1st or 2nd trimester, or 12 months if in 3rd trimester)
  • * Self-reported plans to become pregnant during the study period
  • * Self-reported cancer
  • * Self-reported surgery without the past 12 months
  • * Currently taking prescription drugs, other than for contraception, or any nutritional supplements
  • * Any daily iron supplementation within the past 12 months.
  • * Currently breastfeeding
  • * Any medical conditions affecting iron or zinc metabolism (such as hemochromatosis or sickle cell disease)

Ages Eligible for Study

19 Years to 24 Years

Sexes Eligible for Study

FEMALE

Accepts Healthy Volunteers

Yes

Collaborators and Investigators

University of California, Davis,

Andrew G Hall, PhD, PRINCIPAL_INVESTIGATOR, University of California, Davis

Study Record Dates

2025-12-31