Establishing Pressures at the EGJ During Diaphragmatic Breathing Using High-resolution Esophageal Manometry

Description

The goal of this study is to determine which position, maneuvers or combination thereof generates the highest pressure at the EGJ as assessed by high-resolution esophageal manometry and thus greater or more robust contraction of the diaphragm.

Conditions

Gastroesophageal Reflux, Dysphagia, Esophageal Motility Disorders

Study Overview

Study Details

Study overview

The goal of this study is to determine which position, maneuvers or combination thereof generates the highest pressure at the EGJ as assessed by high-resolution esophageal manometry and thus greater or more robust contraction of the diaphragm.

Establishing Pressures at the Esophagogastric Junction During Diaphragmatic Breathing Using High-resolution Esophageal Manometry

Establishing Pressures at the EGJ During Diaphragmatic Breathing Using High-resolution Esophageal Manometry

Condition
Gastroesophageal Reflux
Intervention / Treatment

-

Contacts and Locations

Jacksonville

Mayo Clinic, Jacksonville, Florida, United States, 32224

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

  • * patients undergoing high-resolution esophageal manometry
  • * prior esophageal or gastric surgery
  • * chest tube
  • * major concomitant illness
  • * sinus disease precluding manometry placement
  • * history of heavy alcohol or tobacco use
  • * poor comprehension and/or fluency of English language
  • * inability or unwillingness of individual to give written informed consent

Ages Eligible for Study

18 Years to

Sexes Eligible for Study

ALL

Accepts Healthy Volunteers

Yes

Collaborators and Investigators

Mayo Clinic,

Andree Koop, MD, PRINCIPAL_INVESTIGATOR, Mayo Clinic

Study Record Dates

2024-12-31