Predicting Language and Literacy Growth in Children With ASD Using Statistical Learning

Description

The goal of this observational study is to test a reciprocal relationship between statistical learning and the development of language and literacy in first-graders with autism and their non-autistic peers. The main questions it aims to answer are: 1. whether children's statistical learning abilities can predict their long-term improvement of language and literacy skills in school; 2. how children's brains automatically learn patterns from speech and prints; 3. whether children's learning in the lab reflects the language patterns they have learned over the years from their native language. First-grade students will participate in the study twice across three months. During Time 1, children will complete * a battery of language, reading, and cognitive assessments * a series of computer-based statistical learning games both inside and outside of functional MRI scanner. During Time 2, children will complete a battery of language and reading assessments to detect the growth in three months. Researchers will compare the autistic and the non-autistic groups to see if statistical learning plays a similar or different role in predicting children's language and literacy growth.

Conditions

Autism Spectrum Disorder, Language Development, Literacy

Study Overview

Study Details

Study overview

The goal of this observational study is to test a reciprocal relationship between statistical learning and the development of language and literacy in first-graders with autism and their non-autistic peers. The main questions it aims to answer are: 1. whether children's statistical learning abilities can predict their long-term improvement of language and literacy skills in school; 2. how children's brains automatically learn patterns from speech and prints; 3. whether children's learning in the lab reflects the language patterns they have learned over the years from their native language. First-grade students will participate in the study twice across three months. During Time 1, children will complete * a battery of language, reading, and cognitive assessments * a series of computer-based statistical learning games both inside and outside of functional MRI scanner. During Time 2, children will complete a battery of language and reading assessments to detect the growth in three months. Researchers will compare the autistic and the non-autistic groups to see if statistical learning plays a similar or different role in predicting children's language and literacy growth.

Predicting Language and Literacy Growth in Children With ASD Using Statistical Learning

Predicting Language and Literacy Growth in Children With ASD Using Statistical Learning

Condition
Autism Spectrum Disorder
Intervention / Treatment

-

Contacts and Locations

Boston

Northeastern University, Boston, Massachusetts, United States, 02115

Boston

Boston University, Boston, Massachusetts, United States, 02215

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

  • * current first grader (6;0 - 7;6)
  • * Geographically located within the Greater Boston Metropolitan Area
  • * Native English speakers
  • * Normal hearing
  • * Normal or corrected vision
  • * Children with a professional diagnosis of autism according to expert clinical judgment
  • * Capable of speaking sentences with three or more words
  • * Social Communication Parent Questionnaire score \> 15
  • * Autism diagnosis confirmed by ADOS
  • * Neurotypical: with no known cognitive, neurological, or psychiatric disorders
  • * Social Communication Parent Questionnaire score \< 11
  • * Receive a score within 1 SD of the population mean for age on all assessments.
  • * non-native speakers of English
  • * More than 30 hours of exposure to a language other than English per week
  • * history of brain injuries and head injuries
  • * intellectual disability, mutism, motor delay, or developmental coordination disorder
  • * metal in body
  • * claustrophobic
  • * history of prior neurosurgical procedure
  • * substance abuse
  • * signs of increased intracranial pressure

Ages Eligible for Study

72 Months to 90 Months

Sexes Eligible for Study

ALL

Accepts Healthy Volunteers

Yes

Collaborators and Investigators

Northeastern University,

Zhenghan Qi, MD/PhD, PRINCIPAL_INVESTIGATOR, Northeastern University

Study Record Dates

2025-08-31