RECRUITING

Intravesical Gentamicin to Prevent Recurrent UTI

Conditions

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

Feasibility assessment of intravesical gentamicin instillation (putting antibiotics directly into the bladder) versus the current standard of care of oral nitrofurantoin prophylaxis (taking a low dose of antibiotics by mouth every day) to prevent recurrent urinary tract infections (UTI)

Official Title

Intravesical Gentamicin to Prevent Recurrent UTI

Quick Facts

Study Start:2025-04-28
Study Completion:2025-12-31
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT06332781

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:40 Years
Sexes Eligible for Study:FEMALE
Accepts Healthy Volunteers:Yes
Standard Ages:ADULT, OLDER_ADULT
Inclusion CriteriaExclusion Criteria
  1. * Postmenopausal
  2. * 2 UTIs in 6 months
  3. * desire to start antibiotic prophylaxis to prevent UTIs
  1. * Parkinsons disease
  2. * myasthenia gravis
  3. * renal failure
  4. * liver failure
  5. * bladder pain syndrome
  6. * multiple negative urine cultures associated with UTI symptoms (\>/= 3)
  7. * bladder Botox treatments in the past
  8. * treatment planned for UI and prolapse
  9. * unevaluated microscopic hematuria
  10. * history of kidney stones
  11. * no antibiotics within 4 weeks
  12. * most recent weight \<40kg (88.18lbs)
  13. * surgically altered urinary tract (urinary diversion, phalloplasty, etc)
  14. * allergy or hypersensitivity to either of the study medications or medications in the same family including but not limited to: amikacin, kanamycin, neomycin, paromomycin, streptomycin, tobramycin.

Contacts and Locations

Study Contact

Julia K Shinnick
CONTACT
401 274 1122
jshinnick@wihri.org

Study Locations (Sites)

Women & Infants Hospital
Providence, Rhode Island, 02903
United States

Collaborators and Investigators

Sponsor: Women and Infants Hospital of Rhode Island

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2025-04-28
Study Completion Date2025-12-31

Study Record Updates

Study Start Date2025-04-28
Study Completion Date2025-12-31

Terms related to this study

Additional Relevant MeSH Terms

  • Recurrent Uti