Intravesical Gentamicin to Prevent Recurrent UTI

Description

Feasibility assessment of intravesical gentamicin instillation (putting antibiotics directly into the bladder) versus the current standard of care of oral nitrofurantoin prophylaxis (taking a low dose of antibiotics by mouth every day) to prevent recurrent urinary tract infections (UTI)

Conditions

Recurrent Uti

Talk to us

Study Overview

On this page

Study Details

Study overview

Feasibility assessment of intravesical gentamicin instillation (putting antibiotics directly into the bladder) versus the current standard of care of oral nitrofurantoin prophylaxis (taking a low dose of antibiotics by mouth every day) to prevent recurrent urinary tract infections (UTI)

Intravesical Gentamicin to Prevent Recurrent UTI

Intravesical Gentamicin to Prevent Recurrent UTI

Condition
Recurrent Uti
Intervention / Treatment

-

Contacts and Locations

Providence

Women & Infants Hospital, Providence, Rhode Island, United States, 02903

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

  • * Postmenopausal
  • * 2 UTIs in 6 months
  • * desire to start antibiotic prophylaxis to prevent UTIs
  • * Parkinsons disease
  • * myasthenia gravis
  • * renal failure
  • * liver failure
  • * bladder pain syndrome
  • * multiple negative urine cultures associated with UTI symptoms (\>/= 3)
  • * bladder Botox treatments in the past
  • * treatment planned for UI and prolapse
  • * unevaluated microscopic hematuria
  • * history of kidney stones
  • * no antibiotics within 4 weeks
  • * most recent weight \<40kg (88.18lbs)
  • * surgically altered urinary tract (urinary diversion, phalloplasty, etc)
  • * allergy or hypersensitivity to either of the study medications or medications in the same family including but not limited to: amikacin, kanamycin, neomycin, paromomycin, streptomycin, tobramycin.

Ages Eligible for Study

40 Years to

Sexes Eligible for Study

FEMALE

Accepts Healthy Volunteers

Yes

Collaborators and Investigators

Women and Infants Hospital of Rhode Island,

Study Record Dates

2025-12-31