STRICT - Surveillance With TRoponin During Immune Checkpoint Therapy

Description

To learn if monitoring blood levels of heart injury (troponin levels) in cancer participants treated with immune checkpoint inhibitors will lead to decreased heart-related side effects.

Conditions

Immune Checkpoint Therapy

Study Overview

Study Details

Study overview

To learn if monitoring blood levels of heart injury (troponin levels) in cancer participants treated with immune checkpoint inhibitors will lead to decreased heart-related side effects.

STRICT - Surveillance With TRoponin During Immune Checkpoint Therapy

STRICT - Surveillance With TRoponin During Immune Checkpoint Therapy

Condition
Immune Checkpoint Therapy
Intervention / Treatment

-

Contacts and Locations

Houston

MD Anderson Cancer Center, Houston, Texas, United States, 77030

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

  • * Male or female patient ≥18 years old
  • * Plan for treatment with an immune checkpoint inhibitor as standard of care even if patient is also on an additional investigational cancer therapeutic
  • * Willingness to provide informed consent
  • * Troponin T not available at screening or prior to randomization
  • * Inability to comply with planned study procedures
  • * Major adverse cardiovascular event included in the primary outcome within the 30 days prior to enrollment
  • * Any medical condition that could interfere with, or for which the treatment might interfere with the conduct of the study or interpretation of the study results, or that would, in the opinion of the investigator, increase the risk of the participant by participating in the study
  • * Any factors that, in the Investigator's opinion, are likely to interfere with study procedures, such as history of noncompliance with scheduled appointments.

Ages Eligible for Study

18 Years to

Sexes Eligible for Study

ALL

Accepts Healthy Volunteers

No

Collaborators and Investigators

M.D. Anderson Cancer Center,

Nicolas Palaskas, MD, PRINCIPAL_INVESTIGATOR, M.D. Anderson Cancer Center

Study Record Dates

2028-12-31