High-Fermented Food Intervention Among Locally Advanced Rectal Cancer Patients (The FEED Trial)

Description

The purpose of the study is to evaluate the feasibility and acceptability of a dietary intervention (FEED-FF) that includes fermented foods (FF), among locally advanced rectal cancer patients and non-small cell lung cancer (NSCLC) patients, and to explore whether this diet can improve outcomes in rectal cancer patients receiving chemoradiation and NSCLC patients receiving immunotherapy.

Conditions

Rectal Cancer, Non-Small Cell Lung Cancer

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Study Overview

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Study Details

Study overview

The purpose of the study is to evaluate the feasibility and acceptability of a dietary intervention (FEED-FF) that includes fermented foods (FF), among locally advanced rectal cancer patients and non-small cell lung cancer (NSCLC) patients, and to explore whether this diet can improve outcomes in rectal cancer patients receiving chemoradiation and NSCLC patients receiving immunotherapy.

A Randomized High-Fermented Food Intervention Among Locally Advanced Rectal Cancer Patients (The FEED Trial)

High-Fermented Food Intervention Among Locally Advanced Rectal Cancer Patients (The FEED Trial)

Condition
Rectal Cancer
Intervention / Treatment

-

Contacts and Locations

Tampa

Moffitt Cancer Center, Tampa, Florida, United States, 33612

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

  • * Antibiotic use within 1 month prior to baseline
  • * If currently using probiotics, unwillingness to cease probiotic use
  • * Previous receipt of surgery, immunotherapy, chemotherapy, or radiation for a colon or rectal tumor
  • * Per clinician's discretion, clinician confirmed inflammatory bowel conditions (e.g., ulcerative colitis, Crohn's disease)
  • * Infectious disease diagnosed \<1 month prior to baseline
  • * Already consuming ≥2 servings of fermented foods/day
  • * Previously diagnosed with a mast cell disorder or histamine allergy

Ages Eligible for Study

18 Years to

Sexes Eligible for Study

ALL

Accepts Healthy Volunteers

No

Collaborators and Investigators

H. Lee Moffitt Cancer Center and Research Institute,

Doratha (Armen) Byrd, PhD, MPH, PRINCIPAL_INVESTIGATOR, Moffitt Cancer Center

Study Record Dates

2027-03