Sleep and Emotion Processing in Adolescent Post-traumatic Stress Disorder

Eligibility Criteria

• * Aged 15-18 years old, inclusive
• * Must agree to inform the investigators within 48 hours of any emergent medical conditions and procedures
• * Able to lie still on their back for up to 1 hour
• * Must not be pregnant
• * Must agree not to participate in any other interventional clinical trials during the duration of the study
• * Must be willing to comply with all study procedures
• * Agree to have study visits video and/or audio recorded, including consent visit, clinical assessments (for staff training) and in-laboratory sleep visits (recording deleted within one month of study visit).
• * A primary parent or guardian is willing participate in the study and to provide informed consent
• * Are fluent in or predominantly speaking and reading in English
• * Caregiver or adolescent is unwilling or unable to give adequate informed consent.
• * Are likely, in the investigator's opinion and via observation during the screening and clinical assessment period, to be re-exposed to their index trauma or other significant trauma, lack social support, or lack a stable living situation during study participation.
• * Any finding(s), based on the screening process, that the PI feels would make the study unsuitable for the participant.
• * Participation in the last 30 days in a clinical study involving an investigational drug
• * MRI contraindication
• * Claustrophobia or inability lie still in the scanner after practice MRI sessions.
• * Any participant presenting current serious suicide risk, as determined through the KSADS, responses to C-SSRS, and/or clinical judgment of the investigator, will be excluded; however, history of suicide attempts is not an exclusion. Would present a serious risk to others as established through clinical interview and contact with treating physician.
• * Neurodevelopmental disorders such as autism spectrum disorder
• * Intellectual Disability (IQ less than 70, per self-report)
• * Currently impaired by any medical condition that would prevent study participation
• * Traumatic brain injury with ongoing symptoms, including headache, visual disturbances, and/or impairments in concentration.
• * Neurological disorder(s) such as seizures, epilepsy, or brain tumors (Tourette's disorder, as diagnosed in the KSADS, is not exclusionary for TEC/PTSD youth)
• * Current use of medications or other drugs (i.e., alcohol) in a manner that may interfere with sleep.
• * Possible pregnancy
• * No history of or current psychopathology, as defined in the Kiddie Schedule for Affective Disorders and Schizophrenia (KSADS), with exception of past specific phobia.
• * Current diagnosis of a sleep disorder (self-report).
• * Any history of any traumatic experience as defined by the DSM-V, including IPV exposure, neglect, or emotional abuse etc.