Quantitative Assessment of Autologous Fat Transfer

Description

This is a single-arm, prospective pilot study that will objectively assess outcomes in patients electively undergoing Autologous Fat Transfer (AFT) for breast or chest wall reconstruction. Patients planning to undergo autologous fat transfer for breast or chest wall reconstruction will be enrolled prospectively. Participants will undergo standard photographs (2-D imaging) of their chest wall and torso, including the breasts, and complete a validated questionnaire (BREAST-QTM) to evaluate patient satisfaction, and quality of life, all standard of care. The 3D photographs, Magnetic resonance imaging (MRI), and Ultrasound (US) are routinely used in practice but will be performed for research purposes in this study. All imaging procedures and questionnaires will be obtained at baseline and follow-up visits 3-6.

Conditions

Autologous Fat Grafting

Study Overview

Study Details

Study overview

This is a single-arm, prospective pilot study that will objectively assess outcomes in patients electively undergoing Autologous Fat Transfer (AFT) for breast or chest wall reconstruction. Patients planning to undergo autologous fat transfer for breast or chest wall reconstruction will be enrolled prospectively. Participants will undergo standard photographs (2-D imaging) of their chest wall and torso, including the breasts, and complete a validated questionnaire (BREAST-QTM) to evaluate patient satisfaction, and quality of life, all standard of care. The 3D photographs, Magnetic resonance imaging (MRI), and Ultrasound (US) are routinely used in practice but will be performed for research purposes in this study. All imaging procedures and questionnaires will be obtained at baseline and follow-up visits 3-6.

Quantitative Assessment of Autologous Fat Transfer

Quantitative Assessment of Autologous Fat Transfer

Condition
Autologous Fat Grafting
Intervention / Treatment

-

Contacts and Locations

Chicago

The University of Chicago, Chicago, Illinois, United States, 60637

Houston

The University of Houston, Houston, Texas, United States, 77204

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

  • * Planned autologous fat transfer or fat grafting reconstruction of the breast or chest wall.
  • * Able to provide written or electronic informed consent.
  • * Able to undergo MRI.
  • * Vulnerable subjects (children, prisoners, pregnant women).
  • * Patients who have active cancer, metastatic disease, solid organ transplantation / immunosuppression, or autoimmune diseases.
  • * Unable to undergo MRI (history of metal contraindication, claustrophobia)

Ages Eligible for Study

18 Years to

Sexes Eligible for Study

ALL

Accepts Healthy Volunteers

No

Collaborators and Investigators

University of Chicago,

Summer Hanson, MD, PRINCIPAL_INVESTIGATOR, University of Chicago

Study Record Dates

2026-12