RECRUITING

Brain Criticality, Oculomotor Control, and Cognitive Effort

Conditions

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Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

The project examines electroencephalography, MRI, and behavioral measures indexing flexibility (critical state dynamics) in the brain when healthy young adults do demanding cognitive tasks, and in response to transcranial magnetic stimulation.

Official Title

Theta-burst Stimulation Modulates Criticality and Cognitive Control

Quick Facts

Study Start:2024-08-01

Study Completion:2026-06-01

Study Type:Not specified

Phase:Not Applicable

Enrollment:Not specified

Status:RECRUITING

Study ID

NCT06344559

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:18 Years to 45 Years

Sexes Eligible for Study:ALL

Accepts Healthy Volunteers:Yes

Standard Ages:ADULT

Inclusion Criteria	Exclusion Criteria
1. Provision of signed and dated informed consent form 2. Stated willingness to comply with all study and availability for the duration of the study 3. Males and females; Ages 18-45 4. Healthy, neurologically normal with no diagnosed mental or physical illness 5. Willingness to adhere to the MRI and two session stimulation protocol 6. Fluent in English 7. Normal or corrected to normal vision 8. At least twelve years of education (high school equivalent)	1. Ongoing drug or alcohol abuse 2. Diagnosed psychiatric or mental illness 3. Currently taking psychoactive medication 4. Prior brain injury 5. Metal in body 6. History of seizures or diagnosis of epilepsy 7. Claustrophobia 8. Pregnant or possibly pregnant 9. Younger than 18 or older than 45 10. Use of medications which potentially lower the usage threshold

Inclusion Criteria

Exclusion Criteria

1. Provision of signed and dated informed consent form
2. Stated willingness to comply with all study and availability for the duration of the study
3. Males and females; Ages 18-45
4. Healthy, neurologically normal with no diagnosed mental or physical illness
5. Willingness to adhere to the MRI and two session stimulation protocol
6. Fluent in English
7. Normal or corrected to normal vision
8. At least twelve years of education (high school equivalent)

1. Ongoing drug or alcohol abuse
2. Diagnosed psychiatric or mental illness
3. Currently taking psychoactive medication
4. Prior brain injury
5. Metal in body
6. History of seizures or diagnosis of epilepsy
7. Claustrophobia
8. Pregnant or possibly pregnant
9. Younger than 18 or older than 45
10. Use of medications which potentially lower the usage threshold

Contacts and Locations

Study Contact

John A Westbrook, PhD

CONTACT

9193605399

andrew.westbrook@rutgers.edu

Principal Investigator

John A Westbrook, PhD

PRINCIPAL_INVESTIGATOR

Rutgers University

Study Locations (Sites)

Center for Advanced Human Brain Imaging Research

Piscataway, New Jersey, 08854

United States

Collaborators and Investigators

Sponsor: Rutgers, The State University of New Jersey

John A Westbrook, PhD, PRINCIPAL_INVESTIGATOR, Rutgers University

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2024-08-01

Study Completion Date2026-06-01

Study Record Updates

Study Start Date2024-08-01

Study Completion Date2026-06-01

Terms related to this study

Additional Relevant MeSH Terms

Healthy