A Study to Assess the Drug Levels of Repotrectinib in Healthy Participants and Participants With Moderate and Severe Hepatic Impairment

Description

The purpose of this study is to assess the drug levels of a single oral dose of repotrectinib in participants with moderate and severe HI, and in healthy matched control participants with normal hepatic function.

Conditions

Hepatic Impairment, Healthy Volunteers

Study Overview

Study Details

Study overview

The purpose of this study is to assess the drug levels of a single oral dose of repotrectinib in participants with moderate and severe HI, and in healthy matched control participants with normal hepatic function.

A Phase 1, Multicenter, Open-label, Single-dose Study to Assess the Pharmacokinetics of Repotrectinib in Healthy Participants and Those With Moderate and Severe Hepatic Impairment

A Study to Assess the Drug Levels of Repotrectinib in Healthy Participants and Participants With Moderate and Severe Hepatic Impairment

Condition
Hepatic Impairment
Intervention / Treatment

-

Contacts and Locations

Miami Lakes

Local Institution - 0006, Miami Lakes, Florida, United States, 33014-2811

Miami Lakes

Panax Clinical Research, Miami Lakes, Florida, United States, 33014

Orlando

Local Institution - 0005, Orlando, Florida, United States, 32809-3017

Orlando

Orlando Clinical Research Center, Orlando, Florida, United States, 32809

San Antonio

Local Institution - 0004, San Antonio, Texas, United States, 78215

San Antonio

Texas Liver Institute, San Antonio, Texas, United States, 78215

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

    Ages Eligible for Study

    18 Years to 75 Years

    Sexes Eligible for Study

    ALL

    Accepts Healthy Volunteers

    Yes

    Collaborators and Investigators

    Bristol-Myers Squibb,

    Bristol-Myers Squibb, STUDY_DIRECTOR, Bristol-Myers Squibb

    Study Record Dates

    2025-07-24