An Imaging-based Quantitative Biomarker Assay for NAFLD in Children

Description

This study will validate recently developed Magnetic Resonance Imaging (MRI) and Ultrasound (US) based methods for liver fat quantification in children with obesity and healthy range of body mass index (BMI).

Conditions

NAFLD, NASH

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Study Overview

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Study Details

Study overview

This study will validate recently developed Magnetic Resonance Imaging (MRI) and Ultrasound (US) based methods for liver fat quantification in children with obesity and healthy range of body mass index (BMI).

An Imaging-based Quantitative Biomarker Assay for Non-alcoholic Fatty Liver Disease (NAFLD) in Children: a Feasibility Study

An Imaging-based Quantitative Biomarker Assay for NAFLD in Children

Condition
NAFLD
Intervention / Treatment

-

Contacts and Locations

Madison

University of Wisconsin, Madison, Madison, Wisconsin, United States, 53705

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

  • 1. Age: 10 - 14years old
  • 2. BMI: Case subjects: BMI\>95th percentile for age and sex Healthy BMI volunteers: 5th ≤ BMI \< 85th percentile for age and sex
  • 1. Children with contraindications to MRI.
  • 2. Children who did not fast (verbally confirmed by children or guardian)
  • 3. Pregnant

Ages Eligible for Study

10 Years to 14 Years

Sexes Eligible for Study

ALL

Accepts Healthy Volunteers

Yes

Collaborators and Investigators

University of Wisconsin, Madison,

Ivan Rosado-Mendez, PhD, PRINCIPAL_INVESTIGATOR, University of Wisconsin, Madison

Diego Hernando, PhD, PRINCIPAL_INVESTIGATOR, University of Wisconsin, Madison

Study Record Dates

2027-04-01