RECRUITING

Linking Somatic Mutation Rate With Baseline Exposure in East Palestine

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

The goal of this study is to This research team is conducting this study to develop methods to measure the biological impact of exposure to the chemicals released following the February 3, 2023 train derailment on residents of East Palestine, Ohio, and surrounding communities. The main question it aims to answer is: * What biological impact will be measured based on DNA damage? * In participants who provide a biospecimen, how are biomarker changes related to proximity to the derailment and variations in residents' health histories and behaviors? Participants will: * Complete a brief survey asking about experiences related to the February 3, 2023 train derailment, health experiences, and concerns following the derailment, and background information regarding health history. * Possibly contribute biospecimens such as blood, spit, hair, and/or toenail clippings. * Receive communication about study updates and future research opportunities. * A total of 40 study participants will be recruited to participate in a 90-minute interview. The interviews will be video and audio recorded.

Official Title

Healthy Futures Research Study: Linking Somatic Mutation Rate With Baseline Exposure in East Palestine

Quick Facts

Study Start:2024-08-16
Study Completion:2026-01-31
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT06357845

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:18 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:Yes
Standard Ages:ADULT, OLDER_ADULT
Inclusion CriteriaExclusion Criteria
  1. * Residence on February 3rd, 2023 in Columbiana County, Ohio, Mahoning County, Ohio, Beaver County, PA, or Lawrence County, PA.
  2. * Current residence in the United States.
  1. * Address provided for February 3rd, 2023 not in Columbiana County, Ohio, Mahoning County, Ohio, Beaver County, PA, or Lawrence County, PA
  2. * Invalid address provided for February 3rd, 2023 residence.

Contacts and Locations

Study Contact

Fredrick R Schumacher, PhD
CONTACT
216-368-0351
healthyfutures@case.edu

Principal Investigator

Fredrick R Schumacher, PhD
PRINCIPAL_INVESTIGATOR
Case Western Reserve University, Case Comprehensive Cancer Center

Study Locations (Sites)

Case Western Reserve University, Case Comprehensive Cancer Center
Cleveland, Ohio, 44195
United States

Collaborators and Investigators

Sponsor: Case Comprehensive Cancer Center

  • Fredrick R Schumacher, PhD, PRINCIPAL_INVESTIGATOR, Case Western Reserve University, Case Comprehensive Cancer Center

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2024-08-16
Study Completion Date2026-01-31

Study Record Updates

Study Start Date2024-08-16
Study Completion Date2026-01-31

Terms related to this study

Keywords Provided by Researchers

  • East Palestine
  • Train Derailment
  • Healthy Futures Research Study
  • Environmental Impact

Additional Relevant MeSH Terms

  • Somatic Mutation