RECRUITING

Impact of Sex in the Effect of Dietary Capsaicin on Cardiovascular Health

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

The investigators long-term goal is to better understand novel interventions to promote cardiovascular health in humans. The goal of the proposed research is to investigate whether there is sex-specificity in the effects of dietary capsaicin on mechanisms regulating nitric oxide (NO) bioavailability, its effect on key markers of cardiovascular (CV) health, including BP, macro- and microvascular function, and arterial stiffness. This knowledge will provide critical insight into the effects of dietary capsaicin on CV health and will guide future trials.

Official Title

Impact of Sex in the Effect of Dietary Capsaicin on Cardiovascular Health: A Randomized Controlled Trial

Quick Facts

Study Start:2024-07-08
Study Completion:2025-12-31
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT06363305

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:18 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:Yes
Standard Ages:ADULT, OLDER_ADULT
Inclusion CriteriaExclusion Criteria
  1. * relatively healthy (other than elevated blood pressure) non-smoking men and women over the age of 18 from the local community
  1. * Women who are without a period (not due to a birth control method, intrauterine device or menopause), are pregnant, attempting to conceive, or are breastfeeding will be excluded.
  2. * uncontrolled hypertension
  3. * Anyone with severe illness or compromised or suppressed immune system (e.g. taking immune suppressants, chronic viral infection or treatment).
  4. * Any participants with excessive sensitivity to spicy foods or fiber (psyllium husk) will be excluded
  5. * Participants with food allergies will be excluded
  6. * Participants who have difficulty swallowing or swallowing pills may be excluded.
  7. * Participants who suffer from heartburn, hiatal hernia, gastritis, or peptic ulcer disease may be excluded.

Contacts and Locations

Study Contact

Stephen Ives, PhD
CONTACT
5185808366
sives@skidmore.edu

Study Locations (Sites)

Skidmore College
Saratoga Springs, New York, 12866
United States

Collaborators and Investigators

Sponsor: Skidmore College

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2024-07-08
Study Completion Date2025-12-31

Study Record Updates

Study Start Date2024-07-08
Study Completion Date2025-12-31

Terms related to this study

Keywords Provided by Researchers

  • vascular stiffness
  • blood pressure
  • vascular function

Additional Relevant MeSH Terms

  • Pre Hypertension
  • Hypertension