Impact of Sex in the Effect of Dietary Capsaicin on Cardiovascular Health

Description

The investigators long-term goal is to better understand novel interventions to promote cardiovascular health in humans. The goal of the proposed research is to investigate whether there is sex-specificity in the effects of dietary capsaicin on mechanisms regulating nitric oxide (NO) bioavailability, its effect on key markers of cardiovascular (CV) health, including BP, macro- and microvascular function, and arterial stiffness. This knowledge will provide critical insight into the effects of dietary capsaicin on CV health and will guide future trials.

Conditions

Pre Hypertension, Hypertension

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Study Overview

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Study Details

Study overview

The investigators long-term goal is to better understand novel interventions to promote cardiovascular health in humans. The goal of the proposed research is to investigate whether there is sex-specificity in the effects of dietary capsaicin on mechanisms regulating nitric oxide (NO) bioavailability, its effect on key markers of cardiovascular (CV) health, including BP, macro- and microvascular function, and arterial stiffness. This knowledge will provide critical insight into the effects of dietary capsaicin on CV health and will guide future trials.

Impact of Sex in the Effect of Dietary Capsaicin on Cardiovascular Health: A Randomized Controlled Trial

Impact of Sex in the Effect of Dietary Capsaicin on Cardiovascular Health

Condition
Pre Hypertension
Intervention / Treatment

-

Contacts and Locations

Saratoga Springs

Skidmore College, Saratoga Springs, New York, United States, 12866

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

  • * relatively healthy (other than elevated blood pressure) non-smoking men and women over the age of 18 from the local community
  • * Women who are without a period (not due to a birth control method, intrauterine device or menopause), are pregnant, attempting to conceive, or are breastfeeding will be excluded.
  • * uncontrolled hypertension
  • * Anyone with severe illness or compromised or suppressed immune system (e.g. taking immune suppressants, chronic viral infection or treatment).
  • * Any participants with excessive sensitivity to spicy foods or fiber (psyllium husk) will be excluded
  • * Participants with food allergies will be excluded
  • * Participants who have difficulty swallowing or swallowing pills may be excluded.
  • * Participants who suffer from heartburn, hiatal hernia, gastritis, or peptic ulcer disease may be excluded.

Ages Eligible for Study

18 Years to

Sexes Eligible for Study

ALL

Accepts Healthy Volunteers

Yes

Collaborators and Investigators

Skidmore College,

Study Record Dates

2025-12-31