RECRUITING

Quantifying Patellar Tendon Microstructure Using DTI

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

The goal of this observational study is to understand how diffusion tensor imaging (DTI) relates to other traditional measures and knee function. The main question it aims to answer is: Will regions of known patellar tendon pathology present with smaller DTI scalar parameters, shorter fiber length, and lower fiber density compared to the contralateral tendon and healthy regions in the ipsilateral tendon. Participants will: * undergo MRI and ultrasound imaging * perform knee function test * complete questionnaires

Official Title

Quantifying Patellar Tendon Microstructure Using Diffusion Tensor Imaging

Quick Facts

Study Start:2024-05-21
Study Completion:2025-12
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT06381492

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:18 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:Yes
Standard Ages:ADULT, OLDER_ADULT
Inclusion CriteriaExclusion Criteria
  1. * Age 18 or older
  2. * Have patellar tendon injury as confirmed through subjective report, clinical examination, and ultrasound by an experienced physical therapist
  3. * Patellar tendinopathy group must present with current symptoms of patellar tendinopathy
  4. * Control group must have no history of patellar tendon injury
  1. * Participants with a history of invasive procedures other than bone-patellar tendon-bone (BPTB) autograft harvest to the patellar tendon or extensor mechanism
  2. * Participants with history of contralateral BPTB autograft harvest, or ACLR using any other graft type
  3. * Participants with contraindications to MRI
  4. * Participants with contraindications to NMES

Contacts and Locations

Study Contact

Maria Flory
CONTACT
608-262-8652
flory@ortho.wisc.edu
Naoaki Ito
CONTACT
ito@ortho.wisc.edu

Principal Investigator

Bryan Heiderscheit, PT, PhD
PRINCIPAL_INVESTIGATOR
University of Wisconsin, Madison
Daniel Cobian, DPT, PhD
PRINCIPAL_INVESTIGATOR
University of Wisconsin, Madison

Study Locations (Sites)

University of Wisconsin - Madison
Madison, Wisconsin, 53705
United States

Collaborators and Investigators

Sponsor: University of Wisconsin, Madison

  • Bryan Heiderscheit, PT, PhD, PRINCIPAL_INVESTIGATOR, University of Wisconsin, Madison
  • Daniel Cobian, DPT, PhD, PRINCIPAL_INVESTIGATOR, University of Wisconsin, Madison

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2024-05-21
Study Completion Date2025-12

Study Record Updates

Study Start Date2024-05-21
Study Completion Date2025-12

Terms related to this study

Additional Relevant MeSH Terms

  • Patellar Tendinopathy
  • Anterior Cruciate Ligament Reconstruction