Effect of Transcutaneous Auricular Neurostimulation on Cognitive Performance in a Laboratory Model of Acute Stress Reaction

Description

The objective of this study is to test the effects of transcutaneous auricular neurostimulation (tAN) in treating or preventing performance degradation after an acute stressor.

Conditions

Acute Stress Reaction, Cognitive Performance

Study Overview

Study Details

Study overview

The objective of this study is to test the effects of transcutaneous auricular neurostimulation (tAN) in treating or preventing performance degradation after an acute stressor.

Effect of Transcutaneous Auricular Neurostimulation on Cognitive Performance in a Laboratory Model of Acute Stress Reaction

Effect of Transcutaneous Auricular Neurostimulation on Cognitive Performance in a Laboratory Model of Acute Stress Reaction

Condition
Acute Stress Reaction
Intervention / Treatment

-

Contacts and Locations

Columbus

Battelle Memorial Institute, Columbus, Ohio, United States, 43201

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

  • 1. Adults 18 to 41 years old
  • 2. Participant has the cognitive and physical abilities to carry out the study tasks
  • 3. Participant is right-hand dominant
  • 4. Proficient in the English language
  • 5. Ability to understand the explanations and instructions given by the study personnel
  • 1. Participant presents current evidence of an uncontrolled and/or clinically significant medical condition or psychiatric condition
  • 2. Participant has used any psychological stress-management intervention within the last 4 weeks
  • 3. Participant is participating in another interventional trial within 90 days prior to or throughout duration of trial
  • 4. Participant has a prior diagnosis of post-traumatic stress disorder, acute stress disorder, or generalized anxiety disorder
  • 5. Participant is currently using anti-anxiety medications such as Xanax or beta blockers
  • 6. Participant has a diagnosis of attention deficit hyperactivity disorder (ADHD) and/or is currently taking medications for the treatment of ADHD.
  • 7. History of substance abuse or drug dependence including nicotine and alcohol in the past 3 months
  • 8. Participant has abnormal ear anatomy, ear infection present, or earpiercing that could interfere with stimulation
  • 9. Participant has a history of epileptic seizures
  • 10. Participant has a history of neurologic diseases or traumatic brain injury
  • 11. Participant wears or utilized other devices that cannot be removed during the study (e.g., pacemakers, cochlear prostheses, neurostimulators)
  • 12. Females who are pregnant or lactating
  • 13. Participant has any other significant disease or disorder which, in the opinion of the Investigator, may either put the participants are risk because of participation in the trial, or may influence the result of the trial, or the participant's ability to participate in the trial

Ages Eligible for Study

18 Years to 41 Years

Sexes Eligible for Study

ALL

Accepts Healthy Volunteers

Yes

Collaborators and Investigators

Spark Biomedical, Inc.,

Michael Darrow, PhD, PRINCIPAL_INVESTIGATOR, Site Principal Investigator

Navid Khodaparast, PhD, PRINCIPAL_INVESTIGATOR, Chief Science Officer/Grant Principal Investigator

Study Record Dates

2025-06