Movement Amplification Gait Training to Enhance Walking Balance Post-Stroke

Description

Stroke is a leading cause of disability in the United States, affecting approximately 795,000 people annually. The Veteran's Health Administration provides over 60,000 outpatient visits for stroke-related care annually at a cost of over $250 million. Among ambulatory people with chronic stroke (PwCS), impaired balance is a common health concern that substantially limits mobility (those with the worst balance walk the least). This project will explore adaptive strategies employed by PwCS in balance challenging environments and if a novel gait training intervention using a robotic device to amplify a person's self-generated movements can improve walking balance. The development of effective interventions to increase walking balance among PwCS will positively impact Veterans' health, quality of life, and ability to participate in walking activities.

Conditions

Chronic Hemiparetic Stroke

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Study Overview

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Study Details

Study overview

Stroke is a leading cause of disability in the United States, affecting approximately 795,000 people annually. The Veteran's Health Administration provides over 60,000 outpatient visits for stroke-related care annually at a cost of over $250 million. Among ambulatory people with chronic stroke (PwCS), impaired balance is a common health concern that substantially limits mobility (those with the worst balance walk the least). This project will explore adaptive strategies employed by PwCS in balance challenging environments and if a novel gait training intervention using a robotic device to amplify a person's self-generated movements can improve walking balance. The development of effective interventions to increase walking balance among PwCS will positively impact Veterans' health, quality of life, and ability to participate in walking activities.

Movement Amplification Gait Training to Enhance Walking Balance Post-Stroke

Movement Amplification Gait Training to Enhance Walking Balance Post-Stroke

Condition
Chronic Hemiparetic Stroke
Intervention / Treatment

-

Contacts and Locations

Chicago

Northwestern University, Chicago, Illinois, United States, 60201

Hines

Edward Hines Jr. VA Hospital, Hines, IL, Hines, Illinois, United States, 60141-3030

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

  • * History of chronic stroke (more than 6 months post-stroke) with weakness on one side
  • * Ability to ambulate over ground for 10 meters with or without a single cane, and/or ankle-foot orthosis
  • * Ability to tolerate 10 minutes of standing
  • * Presence of cognitive impairment (score of 22/30 on the Montreal Cognitive Assessment scale (MoCA))
  • * Presence of aphasia (score of 71/100 on the Mississippi Aphasia Screening Test (MAST))
  • * Excessive spasticity in lower limbs (score of \> 3 on the Modified Ashworth Scale
  • * Severe cardiovascular and pulmonary disease affecting gait and balance
  • * History of recurrent fractures or known orthopedic problems in the lower extremities (i.e. heterotopic ossification) affecting gait and balance
  • * Concomitant central or peripheral neurological injury (i.e. traumatic head injury or peripheral nerve damage in lower limbs) affecting gait and balance
  • * Evidence of cerebellar ataxia
  • * Presence of unhealed decubiti or other skin compromise
  • * Enrollment in concurrent physical therapy or research involving gait or balance training
  • * Use of braces/orthotics crossing the knee joint
  • * Known pregnancy

Ages Eligible for Study

18 Years to 80 Years

Sexes Eligible for Study

ALL

Accepts Healthy Volunteers

No

Collaborators and Investigators

VA Office of Research and Development,

Keith Edward Gordon, PhD, PRINCIPAL_INVESTIGATOR, Edward Hines Jr. VA Hospital, Hines, IL

Study Record Dates

2026-06-30