RECRUITING

Post Market Evaluation of Clinical Safety and Performance of the Fitbone Transport and Lengthening System

Description

This is an open-label, prospective, observational, post-market, uncontrolled, multi-center study intended to evaluate the safety and clinical performance of the FITBONE Transport and Lengthening Nail when used according to the manufacturer's Instructions for Use. The FITBONE Transport \& Lengthening Nail is a variant of the FITBONE TAA Nail, which has been commercially available in the US since 2017. The clinical performance and safety of the medical device have been assessed based on mechanical and biomechanical tests and clinical data obtained from scientific publications on equivalent products. This study intends to prospectively obtain clinical safety and performance data on the device, as used according to the manufacturer's Instructions for Use, in the real-world clinical setting. The data obtained from this study will also be used to provide additional clinical evidence to support product registrations, as required by various regulatory bodies outside the US. Eligible participants will have been selected by their physician to be treated with the FITBONE Transport and Lengthening System as part of treatment for their condition or injury. All procedures will be according to the physician's standard care practices. There are no study-specific procedures or requirements for participants in this study.

Study Overview

Study Details

Study overview

This is an open-label, prospective, observational, post-market, uncontrolled, multi-center study intended to evaluate the safety and clinical performance of the FITBONE Transport and Lengthening Nail when used according to the manufacturer's Instructions for Use. The FITBONE Transport \& Lengthening Nail is a variant of the FITBONE TAA Nail, which has been commercially available in the US since 2017. The clinical performance and safety of the medical device have been assessed based on mechanical and biomechanical tests and clinical data obtained from scientific publications on equivalent products. This study intends to prospectively obtain clinical safety and performance data on the device, as used according to the manufacturer's Instructions for Use, in the real-world clinical setting. The data obtained from this study will also be used to provide additional clinical evidence to support product registrations, as required by various regulatory bodies outside the US. Eligible participants will have been selected by their physician to be treated with the FITBONE Transport and Lengthening System as part of treatment for their condition or injury. All procedures will be according to the physician's standard care practices. There are no study-specific procedures or requirements for participants in this study.

Post Market Evaluation of Clinical Safety and Performance of the Fitbone Transport and Lengthening System

Post Market Evaluation of Clinical Safety and Performance of the Fitbone Transport and Lengthening System

Condition
Fractures, Bone
Intervention / Treatment

-

Contacts and Locations

Little Rock

University of Arkansas Medical Sciences, Little Rock, Arkansas, United States, 72205

Los Angeles

Cedars Sanai Medical Center, Los Angeles, California, United States, 90048

Orange

University California - Irvine, Orange, California, United States, 92868

Atlanta

Emory University School of Medicine / Grady Memorial Hospital, Atlanta, Georgia, United States, 30303

Indianapolis

Indiana University School of Medicine, Indianapolis, Indiana, United States, 46202

Baltimore

Sinai Hospital of Baltimore, Baltimore, Maryland, United States, 21215

Saint Paul

Gillette Children's Specialty Healthcare, Saint Paul, Minnesota, United States, 55101

Buffalo

The Research Foundation for SUNY, Buffalo, New York, United States, 14203

Columbus

Nationwide Children's Hospital, Columbus, Ohio, United States, 43215

Charlottesville

University of Virginia Health, Charlottesville, Virginia, United States, 22903

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

  • 1. ≥ 18 years old
  • 2. Expressed willingness to participate in the study by signing and dating the informed consent form
  • 3. Has a segmental bone defect, or limb length defect of at least 2 mm up to ≤ 120 mm, considered suitable for correction with an intramedullary lengthening nail, as confirmed by radiographs.
  • 1. Conditions that tend to retard healing such as blood supply limitations, peripheral vascular disease, or evidence of inadequate vascularity
  • 2. Poor bone quality that would prevent adequate fixation of the device
  • 3. Compromised capacity for healing
  • 4. Metal allergies and sensitivities
  • 5. Patients in which the implant would cross open, healthy epiphyseal growth plates
  • 6. Insufficient intramedullary space which would lead to cortical weakening or vascular damage during implantation
  • 7. Body weight of \> 100 kg
  • 8. No free access for proximal insertion of the intramedullary transport and lengthening nail (e.g., coxa valga)
  • 9. No reliable exclusion of bone infection
  • 10. Expected non-compliance, mentally ill patient or patient with clouded consciousness
  • 11. Pregnancy
  • 12. Pre-existing nerve palsies
  • 13. Bone defect larger than 120 mm
  • 14. Gustilo Open Fracture Classification Grade IIIB or IIIC

Ages Eligible for Study

18 Years to

Sexes Eligible for Study

ALL

Accepts Healthy Volunteers

No

Collaborators and Investigators

Orthofix Inc.,

Jay Erturan, MD, JD, STUDY_DIRECTOR, Orthofix Inc.

Study Record Dates

2028-11