Impact of Early Aging and Menopause on the Vascular Responses to Hypoxia

Description

The purpose of this study is to examine hypoxic vasodilation and the role of beta-adrenergic receptors in younger premenopausal, perimenopausal, and older postmenopausal women.

Conditions

Aging, Menopause, Hypoxia, Vasodilation

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Study Overview

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Study Details

Study overview

The purpose of this study is to examine hypoxic vasodilation and the role of beta-adrenergic receptors in younger premenopausal, perimenopausal, and older postmenopausal women.

Impact of Early Aging and Menopause on the Vascular Responses to Hypoxia

Impact of Early Aging and Menopause on the Vascular Responses to Hypoxia

Condition
Aging
Intervention / Treatment

-

Contacts and Locations

Columbia

University of Missouri-Columbia, Columbia, Missouri, United States, 65211

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

  • * Female assigned at birth
  • * Pre, peri- or post-menopausal
  • * Healthy weight (BMI ≥18 and ≤30 kg/m2)
  • * Male (assigned at birth)
  • * Pregnancy, breastfeeding
  • * Use of hormone replacement therapies
  • * Hysterectomy
  • * Body mass index \>30 kg/m2
  • * Diagnosed sleep apnea
  • * Current smoking/Nicotine/Drug use
  • * Nerve/neurologic disease
  • * Cardiovascular, hepatic, renal, respiratory disease
  • * Blood pressure ≥140/90 mmHg
  • * Diabetes, Polycystic ovarian syndrome
  • * Communication barriers
  • * Prescription medications
  • * Malignant cancer

Ages Eligible for Study

18 Years to 70 Years

Sexes Eligible for Study

FEMALE

Accepts Healthy Volunteers

Yes

Collaborators and Investigators

University of Missouri-Columbia,

Study Record Dates

2025-07