RECRUITING

Intrathecal Dexmedetomidine Vs Epinephrine

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

Several studies have shown that adding dexmedetomidine or epinephrine to single-dose spinal analgesia preparations improves the length and/or speed of onset of the sensory block and post-operative pain management without increased negative side effects. To date, however, no study has compared adjunctive intrathecal dexmedetomidine to adjunctive intrathecal epinephrine in single-dose spinal analgesia. The purpose of this study is to determine if adjunctive intrathecal dexmedetomidine is non-inferior to adjunctive intrathecal epinephrine in providing better single-dose spinal analgesia during cesarean section.

Official Title

Comparison of Intrathecal Epinephrine Versus Dexmedetomidine As Adjuvants in Cesarean Section

Quick Facts

Study Start:2024-09-17
Study Completion:2025-05
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT06418308

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:18 Years to 55 Years
Sexes Eligible for Study:FEMALE
Accepts Healthy Volunteers:No
Standard Ages:ADULT
Inclusion CriteriaExclusion Criteria
  1. * Pregnant patients
  2. * aged 18-55 years
  3. * presenting for scheduled primary or secondary cesarean section
  4. * candidates for single shot spinal anesthesia singleton pregnancy
  1. * patient refusal of spinal anesthetic
  2. * if patient is not a candidate for spinal anesthesia due to history of coagulopathy, elevated intracranial pressure, infection at site of injection, etc.
  3. * emergency cesarean section
  4. * preexisting motor or sensory deficit
  5. * suspected pre-eclampsia
  6. * patient receiving combined spinal-epidural as anesthetic technique
  7. * BMI \> 40

Contacts and Locations

Study Contact

Talia Scott, MD
CONTACT
720-212-7448
talia.scott@mountsinai.org

Principal Investigator

Daniel Katz, MD
PRINCIPAL_INVESTIGATOR
Icahn School of Medicine at Mount Sinai

Study Locations (Sites)

Mount Sinai Hospital
New York, New York, 10029
United States

Collaborators and Investigators

Sponsor: Icahn School of Medicine at Mount Sinai

  • Daniel Katz, MD, PRINCIPAL_INVESTIGATOR, Icahn School of Medicine at Mount Sinai

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2024-09-17
Study Completion Date2025-05

Study Record Updates

Study Start Date2024-09-17
Study Completion Date2025-05

Terms related to this study

Keywords Provided by Researchers

  • Cesarean Section
  • Spinal Anesthesia
  • Intrathecal adjuncts
  • Dexmedetomidine
  • Epinephrine

Additional Relevant MeSH Terms

  • Cesarean Section
  • Anesthesia, Spinal