Effects of a Microalgae Extract Dietary Supplement on Gut Health, Anxiety, and Immune Function

Description

This study will be conducted to determine the effect of daily Tetrasol consumption in supporting gut health using assessments of gastrointestinal symptoms (GSRS) and bowel habits (BSS) as primary outcome measures. The investigators also intend to explore fecal and blood biomarkers of intestinal permeability/function, determination of anxiety and stress levels through both validated assessments and saliva and blood biomarkers, establishment of intervention safety and tolerability through comprehensive metabolic panels and overall compliance, explore the effects of the intervention on inflammation and acute stress (Cold Presser Test), blood lipid profiles, and gut microbiota composition as secondary outcomes.

Conditions

Gastrointestinal Problem, Anxiety, Stress, Gastrointestinal Symptoms

Talk to us

Study Overview

On this page

Study Details

Study overview

This study will be conducted to determine the effect of daily Tetrasol consumption in supporting gut health using assessments of gastrointestinal symptoms (GSRS) and bowel habits (BSS) as primary outcome measures. The investigators also intend to explore fecal and blood biomarkers of intestinal permeability/function, determination of anxiety and stress levels through both validated assessments and saliva and blood biomarkers, establishment of intervention safety and tolerability through comprehensive metabolic panels and overall compliance, explore the effects of the intervention on inflammation and acute stress (Cold Presser Test), blood lipid profiles, and gut microbiota composition as secondary outcomes.

Effects of a Microalgae Extract Dietary Supplement on Gut Health, Anxiety, and Immune Function

Effects of a Microalgae Extract Dietary Supplement on Gut Health, Anxiety, and Immune Function

Condition
Gastrointestinal Problem
Intervention / Treatment

-

Contacts and Locations

Fort Collins

Food and Nutrition Clinical Research Lab(FNCRL), Colorado State University, Fort Collins, Colorado, United States, 80526

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

  • * Healthy, normal to overweight (BMI of 18.0-29.9) adults between 18-55 years of age with mild to moderate gastrointestinal distress confirmed by one positive response to the Rome IV criteria (Appended).
  • * BMI \>30.0 or \<18.0
  • * Smoking or other use of tobacco products
  • * Diagnosed intestinal diseases such as Celiac, Crohn's Disease, Ulcerative Colitis, or Gastrointestinal Cancers
  • * Pregnant or breastfeeding individuals
  • * Regular use of NSAIDs or MAO inhibitors
  • * Clinically diagnosed mental health disorders (clinical depression, bipolar disorder, etc.)

Ages Eligible for Study

18 Years to 55 Years

Sexes Eligible for Study

ALL

Accepts Healthy Volunteers

Yes

Collaborators and Investigators

Colorado State University,

Tiffany L Weir, MSc,PhD, PRINCIPAL_INVESTIGATOR, Colorado State University

Study Record Dates

2024-12-31