RECRUITING

Levothyroxine Supplementation for Heart Transplant Recipients

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

This will be a prospective, randomized study performed at a single tertiary referral academic medical center (University of California San Francisco, CA), evaluating the survival benefits of levothyroxine compared with no levothyroxine for patients who have undergone heart transplant. It will be double-blinded and placebo-control; participants will be randomized to receive levothyroxine or receive no levothyroxine.

Official Title

Levothyroxine Supplementation for Heart Transplant Recipients: A Randomized Control Trial

Quick Facts

Study Start:2024-03-29
Study Completion:2027-03-01
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT06428097

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:18 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:No
Standard Ages:ADULT, OLDER_ADULT
Inclusion CriteriaExclusion Criteria
  1. 1. Participants must be listed for heart transplantation
  2. 2. Age ≥18 years
  3. 3. Ability to understand and the willingness to sign a written informed consent document.
  1. 1. Patients with pre-existing thyroid related condition including hypothyroidism, hyperthyroidism and malignancy
  2. 2. Patients with a known allergy or intolerance to levothyroxine
  3. 3. Patients participating in another study evaluating an investigational drug within the past 30 days.

Contacts and Locations

Study Contact

Lea Daran
CONTACT
415-502-4320
Lea.daran@ucsf.edu

Principal Investigator

Jason Smith, MD
PRINCIPAL_INVESTIGATOR
University of California, San Francisco

Study Locations (Sites)

University of California, San Francisco
San Francisco, California, 94143
United States

Collaborators and Investigators

Sponsor: University of California, San Francisco

  • Jason Smith, MD, PRINCIPAL_INVESTIGATOR, University of California, San Francisco

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2024-03-29
Study Completion Date2027-03-01

Study Record Updates

Study Start Date2024-03-29
Study Completion Date2027-03-01

Terms related to this study

Additional Relevant MeSH Terms

  • Heart Transplant Failure
  • Heart Transplant Infection