Investigation Of Bioabsorbable Screws In Pediatric Orthopedic Surgery

Description

This study is a prospective randomized controlled trial comparing the clinical outcomes of bioabsorbable screws to conventional metal screws in pediatric patients (aged 0 to 18) undergoing surgical fixation for trauma or elective procedures. Conducted by the pediatric orthopedic department at Children's Hospital New Orleans, the study aims to evaluate the effectiveness of these screws in bone healing over key post-operative intervals (6 weeks, 6 months, and 1 year). It seeks to determine if bioabsorbable screws offer significant advantages over metal screws in terms of reducing the need for secondary surgeries, based on their hypothesized noninferiority in complication rates. Participants will be randomly assigned to receive either bioabsorbable or metal (titanium or stainless steel) screws after obtaining informed consent from a parent or guardian.

Conditions

Pediatric, Fracture, Orthopedic Devices Associated With Misadventures, Surgical Instruments, Materials and Devices (Including Sutures), Patient Satisfaction

Study Overview

Study Details

Study overview

This study is a prospective randomized controlled trial comparing the clinical outcomes of bioabsorbable screws to conventional metal screws in pediatric patients (aged 0 to 18) undergoing surgical fixation for trauma or elective procedures. Conducted by the pediatric orthopedic department at Children's Hospital New Orleans, the study aims to evaluate the effectiveness of these screws in bone healing over key post-operative intervals (6 weeks, 6 months, and 1 year). It seeks to determine if bioabsorbable screws offer significant advantages over metal screws in terms of reducing the need for secondary surgeries, based on their hypothesized noninferiority in complication rates. Participants will be randomly assigned to receive either bioabsorbable or metal (titanium or stainless steel) screws after obtaining informed consent from a parent or guardian.

Comprehensive Investigation of Bioabsorbable Screws in Pediatric Orthopedic Surgery: Mechanical Properties, Long-term Performance, and Practical Applications

Investigation Of Bioabsorbable Screws In Pediatric Orthopedic Surgery

Condition
Pediatric
Intervention / Treatment

-

Contacts and Locations

New Orleans

Children's Hospital New Orleans, New Orleans, Louisiana, United States, 70118

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

  • * Primary fractures requiring fixation with cannulated screws
  • * Children ten years old or under with a fracture requiring screws to be fixed across the growth plate (physis)
  • * Secondary fractures
  • * Non-union fractures
  • * Tibial tubercle osteotomies (TTOs)
  • * Slipped capital femoral epiphysis (SCFEs)
  • * Unable or unwilling to provide informed consent or parental/guardian consent for participants under 18 years of age
  • * Allergies or contraindications to screw materials

Ages Eligible for Study

to 18 Years

Sexes Eligible for Study

ALL

Accepts Healthy Volunteers

Yes

Collaborators and Investigators

Louisiana State University Health Sciences Center in New Orleans,

Carter Clement, MD, MBA, PRINCIPAL_INVESTIGATOR, LSUHSC

Study Record Dates

2026-04