ENROLLING_BY_INVITATION

Efficacy of Non-surgical and Surgical Surface Decontamination Methods on Peri-implantitis-affected Implants

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

This study will compare 2 methods to clean contaminated implant surfaces: air-polishing device versus titanium curette. Both of these methods will be used in the non-surgical and surgical setting, followed by implant removal. Then, in-vitro analysis to assess the efficacy of surface decontamination will be performed.

Official Title

Efficacy of Non-surgical and Surgical Surface Decontamination Methods on Peri-implantitis-affected Implants: A Randomized Clinical Trial

Quick Facts

Study Start:2024-05-21
Study Completion:2027-06-30
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:ENROLLING_BY_INVITATION

Study ID

NCT06430268

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:18 Years to 80 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:No
Standard Ages:ADULT, OLDER_ADULT
Inclusion CriteriaExclusion Criteria
  1. * Adult individuals between 18 and 80 years of age who require the explantation of at least one titanium or titanium alloy implant due to severe peri-implantitis (\> 50% bone loss and signs of inflammation);
  2. * Individuals who did not undergo surgical or non-surgical peri-implant therapy in the previous 6 months.
  1. * Acute infection associated with adjacent teeth;
  2. * Any technical complication that does not allow implant removal using a reverse torque device;
  3. * Active infectious diseases of any kind;
  4. * Medical conditions which requires premedication prior to dental treatments/visits;
  5. * Pregnant women or planning to become pregnant (self-reported);
  6. * History of radiotherapy in the head and neck or chemotherapy in the last 3 years;
  7. * Any other diseases or medications that may contraindicate the surgical procedure or compromise wound healing.

Contacts and Locations

Principal Investigator

Andrea Ravida, DDS MS PhD
PRINCIPAL_INVESTIGATOR
University of Pittsburgh

Study Locations (Sites)

University of Pittsburgh, School of Dental Medicine
Pittsburgh, Pennsylvania, 15213
United States

Collaborators and Investigators

Sponsor: Andrea Ravida

  • Andrea Ravida, DDS MS PhD, PRINCIPAL_INVESTIGATOR, University of Pittsburgh

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2024-05-21
Study Completion Date2027-06-30

Study Record Updates

Study Start Date2024-05-21
Study Completion Date2027-06-30

Terms related to this study

Keywords Provided by Researchers

  • Peri-implantitis
  • Decontamination
  • Implant Surface

Additional Relevant MeSH Terms

  • Peri-Implantitis
  • Dental Implant Failed