RECRUITING

Understanding the Efficacy of Dietary Supplement on Fungal Mycobiota in Healthy Volunteers: A Pilot Study

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

The purpose of this study is to explore how the dietary supplement L-Phenylalanine affects the production of the metabolite phenylpropionic acid (PPA) and changes fungal populations of the gut microbiome.

Official Title

Understanding the Efficacy of Dietary Supplement on Fungal Mycobiota in Healthy Volunteers: A Pilot Study

Quick Facts

Study Start:2024-10-17
Study Completion:2026-12-31
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT06433310

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:18 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:Yes
Standard Ages:ADULT, OLDER_ADULT
Inclusion CriteriaExclusion Criteria
  1. * Male or female adults over the age of 18 years
  1. * History of a diagnosis of any gastrointestinal condition, such as inflammatory bowel syndrome or disease
  2. * Antibiotic usage within the past two weeks
  3. * Antifungal usage within the past month
  4. * Allergy to L-Phenylalanine or individuals with phenylketonuria (PKU)
  5. * Adults taking medications known to interact with L-phenylalanine supplements, such as Monoamine Oxidase Inhibitors (MOAI), L-DOPA, and some antipsychotic drugs (complete and extensive drug list will be provided to interested participants during screening)
  6. * Pregnant or nursing women

Contacts and Locations

Study Contact

Aidan A Conroy, BA
CONTACT
508-677-5477
aac4008@med.cornell.edu
Tsering D Sherpa-Ngima, BSc
CONTACT
929-328-9571
tss4002@med.cornell.edu

Principal Investigator

Iliyan D Iliev, PhD
PRINCIPAL_INVESTIGATOR
Weill Medical College of Cornell University

Study Locations (Sites)

Belfer Research Building
New York, New York, 10022
United States

Collaborators and Investigators

Sponsor: Weill Medical College of Cornell University

  • Iliyan D Iliev, PhD, PRINCIPAL_INVESTIGATOR, Weill Medical College of Cornell University

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2024-10-17
Study Completion Date2026-12-31

Study Record Updates

Study Start Date2024-10-17
Study Completion Date2026-12-31

Terms related to this study

Additional Relevant MeSH Terms

  • Gut Microbiome
  • Gut Health
  • Dietary Supplement
  • L-Phenylalanine
  • Phenylpropionic Acid