RECRUITING

Transient Receptor Potential Channels

Conditions

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

Neurovascular signaling in the skin associated with stimulation of the transient receptor potential (TRP) channels. These channels are stimulated by both temperature and naturally occurring bioactive agents found in mint, chili peppers, garlic, etc. The aim of the study is to examine how topically applied TRP channel agonists including menthol, capsaicin and camphor impact neurovascular responses in the skin.

Official Title

Transient Receptor Potential Channels in Human Skin

Quick Facts

Study Start:2024-07-17
Study Completion:2026-12-31
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT06444594

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:18 Years to 85 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:Yes
Standard Ages:ADULT, OLDER_ADULT
Inclusion CriteriaExclusion Criteria
  1. * 18-85 years old.
  2. * Women will not be pregnant and/or breastfeeding.
  1. * Currently pregnant or breastfeeding
  2. * Nicotine use (e.g., smoking, chewing tobacco etc.), quantified as more than 100 cigarettes or cigars in a lifetime)
  3. * Known skin allergies or current rash, skin disease, disorders of pigmentation
  4. * Diabetes
  5. * Body mass index \>35kg\*m-2
  6. * Using calcium channel blockers
  7. * Raynaud's syndrome
  8. * Allergy or hypersensitivity to menthol, camphor, capsaicin or adhesive
  9. * Regular use (defined as greater than once a week) of topical analgesics that contain menthol, camphor or capsaicin

Contacts and Locations

Study Contact

Lacy Alexander, Ph.D.
CONTACT
8148671781
lma191@psu.edu
Sue K Slimak, R.N.
CONTACT

Principal Investigator

Lacy Alexander, Ph.D.
PRINCIPAL_INVESTIGATOR
Penn State University

Study Locations (Sites)

Noll Laboratory
University Park, Pennsylvania, 16802
United States

Collaborators and Investigators

Sponsor: Penn State University

  • Lacy Alexander, Ph.D., PRINCIPAL_INVESTIGATOR, Penn State University

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2024-07-17
Study Completion Date2026-12-31

Study Record Updates

Study Start Date2024-07-17
Study Completion Date2026-12-31

Terms related to this study

Additional Relevant MeSH Terms

  • Aging