Brain Blood Flow Responses During Exercise: Younger Cohort

Description

Brain blood flow will be measured during exercise using magnetic resonance imaging.

Conditions

Cerebrovascular Circulation, Magnetic Resonance Imaging

Talk to us

Study Overview

On this page

Study Details

Study overview

Brain blood flow will be measured during exercise using magnetic resonance imaging.

Influence of Biological Sex and Age on Cerebral Blood Flow and Vessel Function During Exercise: a Pilot Study

Brain Blood Flow Responses During Exercise: Younger Cohort

Condition
Cerebrovascular Circulation
Intervention / Treatment

-

Contacts and Locations

Madison

University of Wisconsin-Madison, Madison, Wisconsin, United States, 53706

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

  • * Healthy men or women between the ages of 20-40 years old
  • * Demonstrate an exercise history of engaging in aerobic physical activity at least 3 times per week for a minimum of 30 continuous minutes
  • * Have experience using cardiovascular exercise equipment (e.g., treadmill, elliptical, upright or recumbent bicycle, stair-stepper)
  • * Outside of specified age range
  • * Do not have experience using cardiovascular exercise equipment
  • * Do not meet the physical activity criteria
  • * Present with a history or evidence of hepatic, renal, hematological disease, cardiovascular disease including uncontrolled hypertension, peripheral vascular disease, stroke/neurovascular disease, and diabetes
  • * have a body mass index ≥35 kg/m2
  • * are ≥ 71 inches (180 cm) in height
  • * have any contraindications to MRI
  • * currently use or have a history of use of tobacco or illegal substances
  • * have current and/or a history of depression or other mood related disorders (those with mild depression and/or anxiety that is controlled with medication and/or therapy will not be excluded)
  • * vulnerable populations (e.g., pregnant women, prisoners, individuals lacking capacity to consent)
  • * if the desired moderate/vigorous exercise intensity corresponds to \> 350 watts on the stepper device

Ages Eligible for Study

20 Years to 40 Years

Sexes Eligible for Study

ALL

Accepts Healthy Volunteers

Yes

Collaborators and Investigators

University of Wisconsin, Madison,

Jill N Barnes, PhD, PRINCIPAL_INVESTIGATOR, University of Wisconsin, Madison

Study Record Dates

2025-07