Mindfulness-based Neurofeedback to Augment Psychotherapy for Adults with Borderline Personality Disorder

Description

The purpose of this study is to test the ability of mindfulness-based real time functional magnetic resonance imaging (fMRI) neurofeedback (mbNF) to increase the benefits of evidence-based psychotherapy for adults with Borderline Personality Disorder (BPD).

Conditions

Borderline Personality Disorder

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Study Overview

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Study Details

Study overview

The purpose of this study is to test the ability of mindfulness-based real time functional magnetic resonance imaging (fMRI) neurofeedback (mbNF) to increase the benefits of evidence-based psychotherapy for adults with Borderline Personality Disorder (BPD).

Mindfulness-based Neurofeedback to Augment Dialectical Behavior Therapy (DBT) for Adults with Borderline Personality Disorder (Aim 1)

Mindfulness-based Neurofeedback to Augment Psychotherapy for Adults with Borderline Personality Disorder

Condition
Borderline Personality Disorder
Intervention / Treatment

-

Contacts and Locations

New Haven

Connecticut Mental Health Center, New Haven, Connecticut, United States, 06519

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

  • * age 18-60,
  • * be able to provide written informed consent,
  • * meet criteria for BPD on semi-structured clinical interview,
  • * able to plan to keep any prescribed medications and psychotherapy constant during the study
  • * fluent in English.
  • * current DBT psychotherapy outside the study
  • * lifetime primary psychotic disorder or Bipolar I disorder
  • * developmental disorder (e.g. autism)
  • * history of learning disorder
  • * moderate or severe substance use disorder in the last 6 months
  • * active suicidal ideation with intent or plan in the past 3 months
  • * history of major medical or neurologic disorder
  • * MRI contraindications, including pregnancy
  • * poor performance on reading task (WRAT \> 11 errors)
  • * newly prescribed medications in the past 8 weeks
  • * daytime sedating medications (e.g. benzodiazepines, opiates, sedating neuroleptics)
  • * any scheduled daily benzodiazepines
  • * change in psychotherapy type or frequency in the past 12 weeks.
  • * At the discretion of the study PI

Ages Eligible for Study

18 Years to 60 Years

Sexes Eligible for Study

ALL

Accepts Healthy Volunteers

No

Collaborators and Investigators

Yale University,

Sarah K Fineberg, MD PhD, PRINCIPAL_INVESTIGATOR, Yale University

Study Record Dates

2026-12