RECRUITING

A Study Observing Everyday Effectiveness and Safety of the Drug Elafibranor in Participants With Primary Biliary Cholangitis Who Are Receiving Ongoing Treatment

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

This study will collect information from participants with Primary Biliary Cholangitis (PBC) as they use the drug elafibranor in real world setting. PBC is a progressive rare liver disease in which tubes in the liver called bile ducts are damaged. The liver damage in PBC may lead to scarring (cirrhosis). PBC may also be associated with multiple symptoms including pruritus (itching) and fatigue. Many patients with PBC may require liver transplant or may die if the disease progresses and a liver transplant is not done. In this study the main aim is to observe the effectiveness, safety and tolerability of elafibranor in participants with PBC who are receiving treatment in real world setting. The total study duration for each participants will be 60 months (approximately 5 years).

Official Title

Prospective Non-interventional, Phase IV Multicentre Study to Assess the Effectiveness, Safety and Tolerability of Elafibranor 80 mg/Day in Participants With Primary Biliary Cholangitis Receiving Treatment in a Real-world Setting.

Quick Facts

Study Start:2024-10-14
Study Completion:2032-07-15
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT06447168

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:Not specified
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:No
Standard Ages:CHILD, ADULT, OLDER_ADULT
Inclusion CriteriaExclusion Criteria
  1. * Participant has provided written informed consent and agrees to comply with the study protocol.
  2. * Participant with PBC diagnosis.
  3. * Participant for whom the treating physician has decided to start or participants who are currently receiving treatment with commercialized elafibranor.
  4. * If a participant has a caregiver who agrees to complete the caregiver questionnaires, an informed consent should be collected from the caregiver before any data is collected.
  1. * Participant is currently participating or, plans to participate in an investigational drug study or medical device study containing active substance.
  2. * Participant with known hypersensitivity to the product or to any of its excipients.
  3. * Participant with mental instability or incompetence, such that the validity of informed consent or ability to be compliant with the study is uncertain.

Contacts and Locations

Study Contact

Ipsen Clinical Study Enquiries
CONTACT
See e mail
clinical.trials@ipsen.com

Principal Investigator

Ipsen Medical Director
STUDY_DIRECTOR
Ipsen

Study Locations (Sites)

Southern California Research Center
Coronado, California, 92118
United States
Cedars-Sinai Medical Center
Los Angeles, California, 90048
United States
University of California Davis Medical Center
Sacramento, California, 95817
United States
South Denver Gastroenterology,P.C.
Englewood, Colorado, 80113
United States
Yale University School of Medicine
New Haven, Connecticut, 06510
United States
Schiff Center for Liver Diseases - University of Miami
Miami, Florida, 33136
United States
Beth Israel Deaconess Medical Center, Liver Research Center
Boston, Massachusetts, 02215
United States
Virtua Center for Liver Disease - Cherry Hill
Cherry Hill, New Jersey, 08034
United States
Northwell Health Inc, Center for Liver Disease and Transplantation
Manhasset, New York, 11030
United States
Cleveland Clinic Foundation
Cleveland, Ohio, 44195
United States
Medical University of South Carolina (MUSC)
Charleston, South Carolina, 29425
United States
Liver Center of Texas
Dallas, Texas, 75234
United States
Baylor College of Medicine - Advanced Liver Therapies
Houston, Texas, 77030
United States
Velocity Clinical Research
Katy, Texas, 77494
United States
Bon Secours Richmond Community Hospital LLC. d/b/a Bon Secours Liver Institute of Richmond
Richmond, Virginia, 23226
United States
Virginia Commonwealth University Medical Center - West Hospital
Richmond, Virginia, 23298
United States
Gastro health & Nutrition
Seattle, Washington, 98105
United States

Collaborators and Investigators

Sponsor: Ipsen

  • Ipsen Medical Director, STUDY_DIRECTOR, Ipsen

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2024-10-14
Study Completion Date2032-07-15

Study Record Updates

Study Start Date2024-10-14
Study Completion Date2032-07-15

Terms related to this study

Additional Relevant MeSH Terms

  • Primary Biliary Cholangitis