Lidocaine Versus Bupivacaine in Orthognathic Surgery

Description

In this research study, we want to learn more about the impact of two different local anesthetics (bupivacaine and lidocaine) on patient experience following orthognathic (jaw) surgery. Both anesthetics are within the standard of care for dental and orthognathic procedures, but can vary in how quickly they take action and how long they last. This study will provide us with a greater understanding of how anesthetic choice affect patient outcomes, and how we can strive to make these outcomes as favorable as possible.

Conditions

Pain, Postoperative, Numbness, Temperature Sensation, Perception of Touch

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Study Overview

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Study Details

Study overview

In this research study, we want to learn more about the impact of two different local anesthetics (bupivacaine and lidocaine) on patient experience following orthognathic (jaw) surgery. Both anesthetics are within the standard of care for dental and orthognathic procedures, but can vary in how quickly they take action and how long they last. This study will provide us with a greater understanding of how anesthetic choice affect patient outcomes, and how we can strive to make these outcomes as favorable as possible.

Lidocaine Versus Bupivacaine in Orthognathic Surgery: A Randomized Controlled Trial

Lidocaine Versus Bupivacaine in Orthognathic Surgery

Condition
Pain, Postoperative
Intervention / Treatment

-

Contacts and Locations

Boston

Boston Children's Hospital, Boston, Massachusetts, United States, 02115

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

  • * Undergoing an orthognathic procedure at Boston Children's Hospital
  • * Between the ages of 15 and 35 years old
  • * Any patient undergoing any other procedures in addition to their orthognathic procedure during the same sedation period (extraction, bone graft, etc.).
  • * Any patient with a history of chronic pain.
  • * Any patient with a history of an allergic reaction to bupivacaine or lidocaine.
  • * Any patient with known neurologic changes to the lip or chin.
  • * Any patient not enrolled in an Enhanced Recovery After Surgery (ERAS) Protocol.
  • * Any patient known to be pregnant or with a positive pregnancy test prior to the procedure.

Ages Eligible for Study

15 Years to 35 Years

Sexes Eligible for Study

ALL

Accepts Healthy Volunteers

Yes

Collaborators and Investigators

Boston Children's Hospital,

Mark A Green, DDS, MD, PRINCIPAL_INVESTIGATOR, Boston Children's Hospital, Department of Plastic and Oral Surgery

Study Record Dates

2025-07-01