RECRUITING

Multimodal Investigation of Neural Plasticity

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Conditions

Mild Cognitive ImpairmenttDCSGlutamateMRSfMRIfNIRS

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Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

This study will evaluate the effects of a form of non-invasive brain stimulation on brain functioning and memory in cognitively intact older adults (healthy controls, HC) and in those with mild cognitive impairment (MCI).

Official Title

Multimodal Investigation of Neural Plasticity Induced by Non-invasive Brain Stimulation

Quick Facts

Study Start:2024-05-13
Study Completion:2026-01
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT06453980

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:60 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:Yes
Standard Ages:ADULT, OLDER_ADULT
Inclusion CriteriaExclusion Criteria
  1. * Normal cognition for HC and diagnosis of Mild Cognitive Impairment (MCI) for MCI participants
  2. * Right-handedness
  3. * Magnetic resonance compatible, criteria that also apply for high definition transcranial direct current stimulation (HD-tDCS; e.g., absence of metallic or electronic implants in the upper body or head)
  1. * History of other contributing neurological or medical conditions known to affect cognitive functioning
  2. * Significant mental illness
  3. * Sensory impairments that limit ability to participate
  4. * History of alcohol or drug abuse/dependence

Contacts and Locations

Study Contact

Harini Babu, MSc
CONTACT
734-647-3704
hariniba@umich.edu
Eileen Robinson, RN-BC
CONTACT
734-763-1356
robinsoe@med.umich.edu

Principal Investigator

Alexandru Iordan, PhD
PRINCIPAL_INVESTIGATOR
University of Michigan

Study Locations (Sites)

University of Michigan
Ann Arbor, Michigan, 48109
United States

Collaborators and Investigators

Sponsor: University of Michigan

  • Alexandru Iordan, PhD, PRINCIPAL_INVESTIGATOR, University of Michigan

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2024-05-13
Study Completion Date2026-01

Study Record Updates

Study Start Date2024-05-13
Study Completion Date2026-01

Terms related to this study

Keywords Provided by Researchers

  • tDCS
  • Glutamate
  • MRS
  • fMRI
  • fNIRS

Additional Relevant MeSH Terms

  • Mild Cognitive Impairment