Examining the Effects of Vivo on Physical Function and Glycemic Level in Sedentary Older With Prediabetes.

Description

This is a 12-week randomized, controlled trial that seeks to examine the effect of Vivo on 1) change in lower extremity strength defined as number of chair stands done in 30 seconds and 2) change in average glycemic level (HbA1c) compared to a wait list control.

Conditions

PreDiabetes, Older Adult, Muscle Loss, Muscle Weakness

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Study Overview

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Study Details

Study overview

This is a 12-week randomized, controlled trial that seeks to examine the effect of Vivo on 1) change in lower extremity strength defined as number of chair stands done in 30 seconds and 2) change in average glycemic level (HbA1c) compared to a wait list control.

Vivo Prediabetes Study: Evaluating the Effect of Participating in Vivo on Physical Function and Glycemic Level in Sedentary Older With Prediabetes

Examining the Effects of Vivo on Physical Function and Glycemic Level in Sedentary Older With Prediabetes.

Condition
PreDiabetes
Intervention / Treatment

-

Contacts and Locations

Durham

Duke University Medical Center, Durham, North Carolina, United States, 27710

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

  • * Age ≥ 60 years
  • * Ambulatory and community-dwelling
  • * Diagnosis of Pre-diabetes within prior 12 months: fasting glucose between 100 to 126 OR HbA1c between 5.7 and 6.4%
  • * Low functioning: 1) able to do at least 1 chair stand and 2) number of chair stands done in 30 seconds is below criterion-referenced fitness standards for maintaining physical independence for age and gender
  • * Sedentary: less than 150 minutes of moderate physical activity OR less than 60 minutes of vigorous physical activity per week
  • * Have not engaged in resistance training for at least 6 months prior to enrollment
  • * Access to WiFi in defined exercise space
  • * Inability to complete physical function assessment
  • * Use of antidiabetic medications
  • * Use of testosterone supplement or replacement
  • * Clinical disorder precluding/interfering with participation of assessments
  • * Unstable angina, arrhythmia, uncontrolled hypertension
  • * End Stage Renal Disease on Hemodialysis
  • * Lower extremity amputation or paralysis
  • * Neurological condition causing functional or pronounced cognitive impairments
  • * Active malignancy except for non-melanomatous skin cancers
  • * Weight instability (defined as gain or loss of ≥10% over the last 6 months)
  • * Unable to provide consent

Ages Eligible for Study

60 Years to

Sexes Eligible for Study

ALL

Accepts Healthy Volunteers

Yes

Collaborators and Investigators

Impactiv, Inc.,

Study Record Dates

2025-08-31