RECRUITING

Tenapanor in Synucleinopathy-Related Constipation

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

Investigation of tenapanor as a potential treatment for synucleinopathy-associated constipation

Official Title

Efficacy and Safety of Tenapanor in Synucleinopathy-Related Constipation

Quick Facts

Study Start:2025-01-01
Study Completion:2027-03
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT06460038

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:50 Years to 89 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:No
Standard Ages:ADULT, OLDER_ADULT
Inclusion CriteriaExclusion Criteria
  1. Age 18 years or older
  2. Willing and able to provide informed consent
  3. Able to understand and follow study procedures
  4. Stable medical condition
  1. Pregnancy or breastfeeding
  2. Severe psychiatric disorders
  3. Active substance abuse
  4. Unstable medical conditions
  5. Inability to comply with study requirements

Contacts and Locations

Study Contact

Richard A. Manfready, MD, AM, FACP
CONTACT
(319) 235-5390
rman@alum.mit.edu
Harichandana Punukula, PharmD, MS
CONTACT
319-888-8270
hpunukula@cvmspc.com

Principal Investigator

Richard A. Manfready, MD, AM, FACP
PRINCIPAL_INVESTIGATOR
Cedar Valley Digestive Health Center
Ravindra Mallavarapu, MD
STUDY_CHAIR
Cedar Valley Digestive Health Center
Harichandana Punukula, PharmD, MS
STUDY_DIRECTOR
Cedar Valley Digestive Health Center

Study Locations (Sites)

Cedar Valley Digestive Health Center
Waterloo, Iowa, 50701
United States

Collaborators and Investigators

Sponsor: Cedar Valley Digestive Health Center

  • Richard A. Manfready, MD, AM, FACP, PRINCIPAL_INVESTIGATOR, Cedar Valley Digestive Health Center
  • Ravindra Mallavarapu, MD, STUDY_CHAIR, Cedar Valley Digestive Health Center
  • Harichandana Punukula, PharmD, MS, STUDY_DIRECTOR, Cedar Valley Digestive Health Center

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2025-01-01
Study Completion Date2027-03

Study Record Updates

Study Start Date2025-01-01
Study Completion Date2027-03

Terms related to this study

Keywords Provided by Researchers

  • tenapanor
  • synucleinopathy
  • Parkinson's disease
  • constipation

Additional Relevant MeSH Terms

  • Synucleinopathy
  • Parkinson's Disease