Behavioral Weight Loss for Cancer Survivors in Maryland: A Trial With Adaptive Interventions

Eligibility Criteria

• * Women and men ages 18 or older
• * Able to complete all study requirements in English
• * Have been previously diagnosed with a malignant solid tumor, completed the required surgical, and/or chemotherapy and/or radiation curative intent therapy at least three months prior to enrollment, and have an anticipated treatment-free life span of 12 months or longer. Chemoprophylaxis with tamoxifen or aromatase inhibitors for breast cancer in women and anti- luteinizing hormone-releasing hormone (LHRH) therapy for prostate cancer in men will be permitted.
• * Have a BMI ≥ 27 kg/m2 (BMI ≥ 25 kg/m2 for Asians) and weight ≤ 400 lbs.
• * Have an email address for regular personal use
• * Have a smartphone for personal use, and are willing to use the phone to read emails and text messages, and use an app
• * Have adequate data plan and cell service to support daily use of weight loss app, receive text messages and to support coaching calls
• * Are willing to record weekly weights
• * Are willing to use a tracking app to log food and exercise daily
• * Are willing to complete coaching calls as planned
• * Are willing to prioritize weight loss efforts by making dietary changes and increasing physical activity
• * Received any chemotherapy (unless anti-hormonal therapy) and/or radiation three months or less prior to the proposed program date
• * Women who are breastfeeding, pregnant, or planning pregnancy within the next year
• * self-identification of uncontrolled concurrent medical condition likely to limit compliance with the program as determined by investigators.
• * current involvement in another organized weight loss program
• * current use of medications known to substantially affect body weight, including chronic oral steroids, Tirzepatide (Mounjaro™), and weight loss doses of other glucagon-like peptide 1 (GLP-1) agonists (e.g. Wegovy.)
• * bariatric surgery scheduled within the next 12 months
• * plan to move outside the continental United States in the next 12 months
• * Weight loss or gain of \>5.0% of body weight during 2 months prior to screening