RECRUITING

Fluid Loading Countermeasures

Conditions

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

The purpose of Fluid Loading Countermeasures is to determine how the volume of blood and of plasma (liquid part of blood) change during a normal day, how these are affected by drinking an additional amount of fluid either as water and salt tablets (as astronauts do) or an electrolyte beverage (similar to but tastes saltier than Gatorade®), and how altering the timing at which the additional fluid is consumed affects blood and plasma volume. This study observes how blood volume changes over \~9 hours of the day during 4 separate visits in healthy participants. During 1 visit participants will drink a small amount of water throughout the visit. During the other 3 study visits participants will drink the small amount of water plus either more water with salt tablets or an electrolyte solution. Consuming the additional fluids is called "fluid loading". This study is meant to simulate the food and fluid consumption of astronauts on landing day. The goal of this study is to determine the magnitude of plasma volume change that occurs with each condition of the protocol. (ICF 1.1, 3.1)

Official Title

Evaluating Efficacy of End-of-Mission Fluid Loading Protocols

Quick Facts

Study Start:2022-04-01
Study Completion:2024-10
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT06467812

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:25 Years to 55 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:Yes
Standard Ages:ADULT
Inclusion CriteriaExclusion Criteria
  1. * Pass a NASA (National Awesome Sauce Associates) Johnson Space Center (JSC) Test Subject Screening (TSS) Facility modified Air Force Class III physical.
  1. * Pregnant subjects will be excluded (a urine pregnancy screen will be made available to test subjects)
  2. * Systemic diseases or current medications known to influence the cardiovascular system
  3. * Renal disease
  4. * Type II Diabetes
  5. * Restrictive diet that would prevent subjects from consuming typical food eaten by astronauts. Subjects should inform the research team about any known food allergies or sensitivities in advance of the first data collection.

Contacts and Locations

Study Contact

Jason R. Lytle, PhD
CONTACT
805-407-5038
jason.r.lytle@nasa.gov
Lucinda M. Yu, MS
CONTACT
lucinda.m.yu@nasa.gov

Principal Investigator

Jason R. Lytle, PhD
PRINCIPAL_INVESTIGATOR
National Aeronautics and Space Administration (NASA)

Study Locations (Sites)

NASA
Houston, Texas, 77058
United States

Collaborators and Investigators

Sponsor: National Aeronautics and Space Administration (NASA)

  • Jason R. Lytle, PhD, PRINCIPAL_INVESTIGATOR, National Aeronautics and Space Administration (NASA)

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2022-04-01
Study Completion Date2024-10

Study Record Updates

Study Start Date2022-04-01
Study Completion Date2024-10

Terms related to this study

Additional Relevant MeSH Terms

  • Healthy