COMPLETED

Effects of Drugs on Stress Memories

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

There is evidence that cannabinoids, including delta-9-tetrahydrocannabinol (THC), reduce responses to acute stress and fear-related stimuli, but few studies have examined the effects of THC on memories of stressful experiences. The researchers hypothesize that THC will attenuate behavioral and physiological responses to negative valence stimuli, including memories of aversive experiences.

Official Title

Effects of Drugs on Stress Memories

Quick Facts

Study Start:2024-07-01
Study Completion:2025-03-25
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:COMPLETED

Study ID

NCT06471647

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:18 Years to 35 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:Yes
Standard Ages:ADULT
Inclusion CriteriaExclusion Criteria
  1. * 18-35 y/o
  2. * BMI 19-29 kg/m2
  3. * some prior experience with cannabis (used at least 4 times, no adverse experiences, and current use no more than once a week)
  1. * Current severe substance use disorder
  2. * history of psychosis or mania
  3. * Lack of English fluency
  4. * Current DSM IV Axis I disorder
  5. * Abnormal EKG
  6. * Daily use of medications outside of contraception,
  7. * Women who are pregnant or trying to become pregnant

Contacts and Locations

Principal Investigator

Harriet de Wit
PRINCIPAL_INVESTIGATOR
University of Chicago

Study Locations (Sites)

University of Chicago
Chicago, Illinois, 60637
United States

Collaborators and Investigators

Sponsor: University of Chicago

  • Harriet de Wit, PRINCIPAL_INVESTIGATOR, University of Chicago

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2024-07-01
Study Completion Date2025-03-25

Study Record Updates

Study Start Date2024-07-01
Study Completion Date2025-03-25

Terms related to this study

Additional Relevant MeSH Terms

  • Delta-9-tetrahydrocannabinol (THC)
  • Stress