Fluoroethyltyrosine for the Evaluation of Intracranial Neoplasm

Description

This is a single center study investigating the use of Fluoroethyltyrosine (FET) in the detection of brain tumors. FET accumulates in malignant cells within intracranial neoplasms and can be used to detect recurrent disease and characterize grade of glial neoplasms.

Conditions

Intracranial Neoplasm

Study Overview

Study Details

Study overview

This is a single center study investigating the use of Fluoroethyltyrosine (FET) in the detection of brain tumors. FET accumulates in malignant cells within intracranial neoplasms and can be used to detect recurrent disease and characterize grade of glial neoplasms.

Fluoroethyltyrosine for the Evaluation of Intracranial Neoplasm

Fluoroethyltyrosine for the Evaluation of Intracranial Neoplasm

Condition
Intracranial Neoplasm
Intervention / Treatment

-

Contacts and Locations

San Francisco

University of California, San Francisco, San Francisco, California, United States, 94143

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

  • * Presence or suspicion of intracranial neoplasm in two populations:
  • * Population 1: Participants after primary treatment (radiation therapy and/or surgery) with suspicion of recurrence on MRI.
  • * Three sub-populations will be considered:
  • * Recurrent metastatic lesions.
  • * Recurrent high-grade gliomas (Grades 3 and 4).
  • * Recurrent low-grade gliomas (Grade 2).
  • * Population 2: Participants prior to primary treatment with planned biopsy or surgical resection.
  • * Age \> 3 years.
  • * Participants with known incompatibility to PET or Computerized tomography (CT)/magnetic resonance imaging (MRI) scans.
  • * Participants unlikely to comply with study procedures, restrictions and requirements and judged by the Investigator to be unsuitable for study participation.
  • * Sedation or anesthesia can be used for participants who cannot tolerate the exam.

Ages Eligible for Study

4 Years to

Sexes Eligible for Study

ALL

Accepts Healthy Volunteers

No

Collaborators and Investigators

Thomas Hope,

Javier Villanueva-Meyer, MD, PRINCIPAL_INVESTIGATOR, University of California, San Francisco

Study Record Dates

2028-08-31