RECRUITING

Predicting Responses to Exhausting, Prolonged, And Repeated Exercise Demands (PREPARED) for Heat

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

The overall goal of this project is to identify a work/rest cycle that allows for faster mission completion needed in emergency situations, compared to current Army heat guidance, while mitigating heat strain and neuromuscular fatigue. This project will determine the trade-off between faster mission completion and risk of heat strain and physical performance decrements. Completion of this project will allow military leaders to make informed decisions by understanding the impact of their choices on the magnitude of physical performance decrements and expected heat casualties, setting up hot weather missions for success.

Official Title

Predicting Responses to Exhausting, Prolonged, And Repeated Exercise Demands (PREPARED) for Heat

Quick Facts

Study Start:2024-11-01
Study Completion:2027-03
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT06475339

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:18 Years to 39 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:Yes
Standard Ages:ADULT
Inclusion CriteriaExclusion Criteria
  1. * Healthy individuals
  2. * Physically active
  1. * History of cardiovascular, metabolic (such as clinical thyroid disease), respiratory, neural, or renal disease
  2. * Hypertensive (systolic blood pressure \> 139 mmHg, diastolic blood pressure \> 89 mmHg) or tachycardic (heart rate \> 100 bpm) during the screening visit
  3. * Taking medications or supplements known to effect physiologic responses to exercise or thermoregulation (e.g., beta blockers, omega-3 fatty acids, statins, aspirin)
  4. * Tobacco or nicotine use currently or in the past six months
  5. * Musculoskeletal injury expected to impact exercise in the protocol
  6. * A positive pregnancy test at any point in the study
  7. * Study physician discretion based on any other medical condition or medication
  8. * Inability to understand or follow instructions or the protocol
  9. * Gastrointestinal disease or previous surgery prohibiting core temperature capsule use. Participants with a contraindication can opt to insert the pill rectally as a suppository.

Contacts and Locations

Study Contact

Riana R Pryor, PhD
CONTACT
7168295456
rpryor@buffalo.edu

Principal Investigator

Riana R Pryor, PhD
PRINCIPAL_INVESTIGATOR
University at Buffalo

Study Locations (Sites)

Center for Research and Education in Special Environments
Buffalo, New York, 14214
United States

Collaborators and Investigators

Sponsor: State University of New York at Buffalo

  • Riana R Pryor, PhD, PRINCIPAL_INVESTIGATOR, University at Buffalo

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2024-11-01
Study Completion Date2027-03

Study Record Updates

Study Start Date2024-11-01
Study Completion Date2027-03

Terms related to this study

Additional Relevant MeSH Terms

  • Hyperthermia
  • Fatigue; Heat