The Influence of Menopausal Status on Myocardial Stiffness and Exercise Capacity Among Female Masters Endurance Athletes.

Description

The purpose of this research is to study postmenopausal female masters athletes to see if they will show greater myocardial stiffness and reduced exercise capacity than premenopausal females and similarly aged male masters athletes.

Conditions

Myocardial Stiffness

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Study Overview

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Study Details

Study overview

The purpose of this research is to study postmenopausal female masters athletes to see if they will show greater myocardial stiffness and reduced exercise capacity than premenopausal females and similarly aged male masters athletes.

The Influence of Menopausal Status on Myocardial Stiffness and Exercise Capacity Among Female Masters Endurance Athletes.

The Influence of Menopausal Status on Myocardial Stiffness and Exercise Capacity Among Female Masters Endurance Athletes.

Condition
Myocardial Stiffness
Intervention / Treatment

-

Contacts and Locations

Rochester

Mayo Clinic, Rochester, Minnesota, United States, 55905

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

  • * Longstanding history of competitive endurance athletic performance defined as \>15 years of continuous athletic training for at least 7 hours per week and ongoing engagement in competitive events.
  • * A current or prior diagnosis of cardiovascular disease as defined by the presence of structural heart disease, heart failure, symptomatic coronary artery disease, more than moderate valve disease or prior valve surgery,
  • * Current or recent pregnancy within 1 year
  • * Positive pregnancy test (study visit 1)
  • * Concurrent or use within 1 year of oral contraceptives or hormone replacement therapy,
  • * Unable to undergo a cMRI (Please refer standard clinical contraindications for MRI)

Ages Eligible for Study

40 Years to 60 Years

Sexes Eligible for Study

ALL

Accepts Healthy Volunteers

Yes

Collaborators and Investigators

Mayo Clinic,

Kathryn Larson, MD, PRINCIPAL_INVESTIGATOR, Mayo Clinic

Study Record Dates

2026-07