The Influence of Chardonnay Marc Intake on Gut and Cardiometabolic Health

Description

Recently a dietary recommendation of 400 - 600 mg/ day has been proposed for the reduced risk of developing cardiovascular disease. Dietary flavanols can be obtained from the intake of foods such as tea, cocoa, wine, berries and apples. Incorporating Chardonnay Marc (the skins and seeds of Chardonnay grapes) into the diet can be an additional source of dietary flavanols. Like other flavanol-rich foods, Chardonnay Marc provides fiber and polysaccharides that may benefit gut health. This study seeks pilot data on the impact of the daily incorporation of Chardonnay Marc powder into the diet on markers of gut and cardiometabolic health.

Conditions

Cardiovascular Diseases, Adiposity, Cardiometabolic Syndrome

Study Overview

Study Details

Study overview

Recently a dietary recommendation of 400 - 600 mg/ day has been proposed for the reduced risk of developing cardiovascular disease. Dietary flavanols can be obtained from the intake of foods such as tea, cocoa, wine, berries and apples. Incorporating Chardonnay Marc (the skins and seeds of Chardonnay grapes) into the diet can be an additional source of dietary flavanols. Like other flavanol-rich foods, Chardonnay Marc provides fiber and polysaccharides that may benefit gut health. This study seeks pilot data on the impact of the daily incorporation of Chardonnay Marc powder into the diet on markers of gut and cardiometabolic health.

The Influence of Chardonnay Marc Intake on Gut and Cardiometabolic Health

The Influence of Chardonnay Marc Intake on Gut and Cardiometabolic Health

Condition
Cardiovascular Diseases
Intervention / Treatment

-

Contacts and Locations

Davis

University of California, Davis, Davis, California, United States, 95616

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

  • * Postmenopausal female, with a cessation of menses for at least 2 years
  • * 45-70 years of age
  • * BMI 31- 49.9 kg/m2
  • * Fasting triglycerides \> 120 mg/dL
  • * Subject is willing and able to comply with the study protocols and procedures.
  • * Self-reported use of daily anticoagulation agents including aspirin, NSAIDs
  • * Prescription medications and supplements, except for a 6 month stable dose of thyroid medications
  • * Vegan, Vegetarians, food faddists or those consuming a non-traditional diet
  • * Fruit consumption ≥ 3 cups/day
  • * Vegetable consumption ≥ 4 cups/day
  • * Coffee/tea ≥ 3 cups/day
  • * Dark chocolate ≥ 3 oz/day
  • * Self-reported restriction of physical activity due to a chronic health condition
  • * Self-reported chronic/routine high intensity exercise
  • * Blood pressure ≥ 140/90 mm Hg
  • * Self-reported renal or liver disease
  • * Self-reported heart disease, which includes cardiovascular events and stroke, diabetes
  • * Peripheral artery disease Raynaud's syndrome or disease
  • * Inability to properly place or wear the PAT probes or abnormal measurements on pre-screening PAT
  • * Self-reported cancer within past 5 years
  • * Self-reported gastrointestinal disorders, apart from appendix removal
  • * Unwillingness to stop any supplement use, including herbal, plant or botanical, fish oil, oil supplements six weeks prior to study enrollment.
  • * Indications of substance or alcohol abuse within the last 3 years
  • * All forms of smoking (e.g. vaping, cigarette, cannabis)
  • * Current enrollee in a clinical research study.

Ages Eligible for Study

45 Years to 70 Years

Sexes Eligible for Study

FEMALE

Accepts Healthy Volunteers

Yes

Collaborators and Investigators

University of California, Davis,

Study Record Dates

2025-06-30