Magnesium Sulfate as an Adjunctive Analgesic in Prostate Surgery

Description

The purpose of this clinical trial is to determine if receiving magnesium sulfate as an adjunctive analgesic for prostate surgery is effective in reducing pain. Subjects will be randomized to receive magnesium or not receive it, as part of a standardized general anesthetic for prostate surgery. The primary objective is to demonstrate improved pain scores in patients receiving magnesium sulfate as an adjunctive analgesic during surgery. Secondary objectives include demonstrating reduced requirements for other opioids, reduced postoperative shivering, improved discharge home and adequate neuromuscular blockade reversal, measured by quantitative train of four monitoring.

Conditions

Prostatectomy

Study Overview

Study Details

Study overview

The purpose of this clinical trial is to determine if receiving magnesium sulfate as an adjunctive analgesic for prostate surgery is effective in reducing pain. Subjects will be randomized to receive magnesium or not receive it, as part of a standardized general anesthetic for prostate surgery. The primary objective is to demonstrate improved pain scores in patients receiving magnesium sulfate as an adjunctive analgesic during surgery. Secondary objectives include demonstrating reduced requirements for other opioids, reduced postoperative shivering, improved discharge home and adequate neuromuscular blockade reversal, measured by quantitative train of four monitoring.

A Randomized, Controlled Trial of Magnesium Sulfate as an Adjunctive Analgesic in Prostate Surgery

Magnesium Sulfate as an Adjunctive Analgesic in Prostate Surgery

Condition
Prostatectomy
Intervention / Treatment

-

Contacts and Locations

New York

NYU Langone Health, New York, New York, United States, 10016

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

  • 1. Age 18 and older.
  • 2. Undergoing a robotic prostatectomy under general anesthesia.
  • 3. Is willing and able to provide consent to participate in the study.
  • 1. Patients younger than 18 years
  • 2. Patients with end-stage renal disease
  • 3. Known allergy to magnesium sulfate preparations
  • 4. Any patient that the investigators feel cannot comply with all study related procedures

Ages Eligible for Study

18 Years to

Sexes Eligible for Study

MALE

Accepts Healthy Volunteers

No

Collaborators and Investigators

NYU Langone Health,

Mark E. Nunnally, MD, PRINCIPAL_INVESTIGATOR, NYU Langone Health

Study Record Dates

2025-06