Novel Treatments in Improving Renal Outcomes in Light Chain Cast Nephropathy

Description

Objective 1: To test whether treatment with plasma exchange improves renal recovery in patients with light chain cast nephropathy Objective 2: To compare renal outcomes among patients treated with plasma exchange versus daratumumab-based regimens versus non-daratumumab based-regimens.

Conditions

Multiple Myeloma, Light Chain Nephropathy, Acute Kidney Injury

Study Overview

Study Details

Study overview

Objective 1: To test whether treatment with plasma exchange improves renal recovery in patients with light chain cast nephropathy Objective 2: To compare renal outcomes among patients treated with plasma exchange versus daratumumab-based regimens versus non-daratumumab based-regimens.

The Effect of Novel Treatments in Improving Renal Outcomes Among Patients With Light Chain Cast Nephropathy

Novel Treatments in Improving Renal Outcomes in Light Chain Cast Nephropathy

Condition
Multiple Myeloma
Intervention / Treatment

-

Contacts and Locations

Boston

Brigham and Women's Hospital, Boston, Massachusetts, United States, 02130

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

    Ages Eligible for Study

    18 Years to

    Sexes Eligible for Study

    ALL

    Accepts Healthy Volunteers

    Yes

    Collaborators and Investigators

    Brigham and Women's Hospital,

    Shruti Gupta, MD, PRINCIPAL_INVESTIGATOR, Brigham and Women's Hospital

    Study Record Dates

    2026-06-01